Genome-wide association study reveals the genetic architecture of root hair length in maize.
Genome-wide association study reveals the genetic architecture of root hair length in maize.
复制标题
全基因组关联研究揭示了玉米根毛长度的遗传结构
DOI：
10.1186/s12864-021-07961-z
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发表时间：
2021-09-14
期刊：
影响因子：
4.4
通讯作者：
He Y
中科院分区：
文献类型：
--
作者：
Liu L;Jiang LG;Luo JH;Xia AA;Chen LQ;He Y
根毛是根表皮细胞生长出来的一种特殊的管状细胞，在营养和水分的获取以及与生物和非生物胁迫的相互作用中起着重要作用。虽然已经发现了许多与根毛发育有关的基因，但根毛生长自然变异的遗传基础从未被探索过。结果利用281个热带、亚热带和温带来源的玉米自交系，分析了玉米根毛长度的表型多样性和遗传基础。我们证明了根毛长度与许多代谢途径和其他农艺性状的显著关联。通过全基因组关联研究（GWAS）将根毛表型与125万个单核苷酸多态性（snp）结合起来，发现了几个与细胞信号传导、极性生长、抗病和各种代谢途径有关的候选基因。结论这些结果说明了玉米根毛长度的遗传基础，提供了可预测的影响根毛生长的候选基因列表，为未来的功能研究提供了宝贵的资源。
BackgroundRoot hair, a special type of tubular-shaped cell, outgrows from root epidermal cell and plays important roles in the acquisition of nutrients and water, as well as interactions with biotic and abiotic stress. Although many genes involved in root hair development have been identified, genetic basis of natural variation in root hair growth has never been explored.ResultsHere, we utilized a maize association panel including 281 inbred lines with tropical, subtropical, and temperate origins to decipher the phenotypic diversity and genetic basis of root hair length. We demonstrated significant associations of root hair length with many metabolic pathways and other agronomic traits. Combining root hair phenotypes with 1.25 million single nucleotide polymorphisms (SNPs) via genome-wide association study (GWAS) revealed several candidate genes implicated in cellular signaling, polar growth, disease resistance and various metabolic pathways.ConclusionsThese results illustrate the genetic basis of root hair length in maize, offering a list of candidate genes predictably contributing to root hair growth, which are invaluable resource for the future functional investigation.
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DOI：
10.1073/pnas.1613499114
发表时间：
2017-06-13
影响因子：
11.1
作者：
Barbez, Elke;Duenser, Kai;Busch, Wolfgang
通讯作者：
Busch, Wolfgang
影响因子：
4.5
作者：
Bruex A;Kainkaryam RM;Wieckowski Y;Kang YH;Bernhardt C;Xia Y;Zheng X;Wang JY;Lee MM;Benfey P;Woolf PJ;Schiefelbein J
通讯作者：
Schiefelbein J
影响因子：
2.7
作者：
Berger, F;Hung, CY;Schiefelbein, J
通讯作者：
Schiefelbein, J
影响因子：
11.6
作者：
Diet, Anouck;Link, Bruce;Ringli, Christoph
通讯作者：
Ringli, Christoph
DOI：
10.1073/pnas.1005366107
发表时间：
2010-10-12
影响因子：
11.1
作者：
Duan, Qiaohong;Kita, Daniel;Wu, Hen-Ming
通讯作者：
Wu, Hen-Ming