Pathways to anxiety-depression comorbidity: A longitudinal examination of childhood anxiety disorders.

Pathways to anxiety-depression comorbidity: A longitudinal examination of childhood anxiety disorders.
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焦虑抑郁共病的途径:儿童焦虑障碍的纵向检查。

DOI:
10.1002/da.22544
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发表时间:
2016-10
影响因子:
7.4
通讯作者:
Beidas, Rinad S.
Beidas, Rinad S.
中科院分区:
医学1区
文献类型:
--
作者:
Wolk, Courtney Benjamin;Carper, Matthew M.;Kendall, Philip C.;Olino, Thomas M.;Marcus, Steven C.;Beidas, Rinad S.

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焦虑症在年轻人中很普遍,并与后来的抑郁症有关。最近的一个模型假设了三种不同的焦虑-抑郁途径。途径1代表年轻人具有焦虑的素质,增加了患抑郁症的风险;途径2描述了具有共同焦虑抑郁素质的青年;途径3是由具有抑郁素质的年轻人组成的,他们因为抑郁障碍而产生焦虑。这是认知行为治疗(CBT)治疗儿童焦虑后,该模型的第一个部分测试。本研究纳入了7 - 19年前(M = 16.24; SD = 3.56)接受CBT治疗的儿童焦虑症患者(N = 66; M = 27.23岁,SD = 3.54)。在治疗前、治疗后以及一次或多次随访期间,通过访谈和自我报告获得有关焦虑(即社交恐惧症(SoP)、分离焦虑障碍(SAD)、广泛性焦虑障碍(GAD))和情绪障碍(即重度抑郁障碍(MDD)和心境恶劣障碍)的信息。没有观察到从SoP、SAD和GAD到后来的抑郁症的途径的证据。治疗反应者证明GAD和SoP随着时间的推移而降低,尽管SoP被观察到具有更慢性和持久的模式。没有观察到儿童焦虑障碍的典型观察途径的证据。未来的研究应该前瞻性地检查CBT治疗反应是否破坏了通常观察到的通路。
Anxiety disorders are prevalent in youth and associated with later depressive disorders. A recent model posits three distinct anxiety-depression pathways. Pathway 1 represents youth with a diathesis to anxiety that increases risk for depressive disorders; Pathway 2 describes youth with a shared anxiety-depression diathesis; and Pathway 3 consists of youth with a diathesis for depression who develop anxiety as a consequence of depression impairment. This is the first partial test of this model following cognitive-behavioral treatment (CBT) for child anxiety. The present study included individuals (N = 66; M age = 27.23 years, SD = 3.54) treated with CBT for childhood anxiety disorders 7 to 19 years (M = 16.24; SD = 3.56) earlier. Information regarding anxiety (i.e., Social Phobia (SoP), Separation Anxiety Disorder (SAD), Generalized Anxiety Disorder (GAD)) and mood disorders (i.e., Major Depressive Disorder (MDD) and dysthymic disorders) was obtained at pretreatment, posttreatment, and one or more follow-up intervals via interviews and self-reports. Evidence of pathways from SoP, SAD, and GAD to later depressive disorders was not observed. Treatment responders evidenced reduced GAD and SoP over time, although SoP was observed to have a more chronic and enduring pattern. Evidence for typically observed pathways from childhood anxiety disorders was not observed. Future research should prospectively examine if CBT treatment response disrupts commonly observed pathways.
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