Plasmonic nanoprobes for SERS biosensing and bioimaging.
Plasmonic nanoprobes for SERS biosensing and bioimaging.
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DOI:
10.1002/jbio.200910015
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发表时间:
2010-01
影响因子:
2.8
通讯作者:
Scaffidi, Jonathan
中科院分区:
文献类型:
--
作者:
Vo-Dinh, Tuan;Wang, Hsin-Neng;Scaffidi, Jonathan
关键词:
This article provides an overview of the development and application of plasmonic nanoprobes developed in our laboratory for biosensing and bioimaging. We describe the use of plasmonics surface-enhanced Raman scattering (SERS) gene probes for the detection of diseases using DNA hybridization to target biospecies (HIV gene, breast cancer genes etc.). For molecular imaging, we describe a hyperspectral surface-enhanced Raman imaging (HSERI) system that combines imaging capabilities with SERS detection to identify cellular components using Raman dye-labeled silver nanoparticles in cellular systems The detection of specific target DNA sequences associated with breast cancer using “molecular sentinel” nanoprobes and the use of a plasmonic nanosensor to monitor pH in single cells are presented and discussed. Plasmonic nanosensors and nanoprobes have been developed as sensitive and selective tolls for environmental monitoring, cellular biosensing, medical diagnostics and high throughput screnning.
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影响因子:
7.4
作者:
Isola, NR;Stokes, DL;Vo-Dinh, T
通讯作者:
Vo-Dinh, T
影响因子:
3.3
作者:
Doering, WE;Nie, SM
通讯作者:
Nie, SM
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3.5
作者:
MOODY, RL;VO-DINH, T;FLETCHER, WH
通讯作者:
FLETCHER, WH
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LEE, PC;MEISEL, D
通讯作者:
MEISEL, D
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7.4
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BELLO, JM;STOKES, DL;VO-DINH, T
通讯作者:
VO-DINH, T