COVID-19 Critical Illness: A Data-Driven Review.
COVID-19 Critical Illness: A Data-Driven Review.
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DOI：
10.1146/annurev-med-042420-110629
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发表时间：
2022-01-27
影响因子：
10.5
通讯作者：
Christie JD
中科院分区：
文献类型：
--
作者：
Ginestra JC;Mitchell OJL;Anesi GL;Christie JD
2019冠状病毒病（COVID-19）大流行给重症监护医学带来了前所未有的挑战，包括对重症监护病房（ICU）资源的极端需求以及对一种新型疾病快速发展的认识。多达三分之一的COVID-19住院患者病情危重。COVID-19危重疾病中最常见的器官衰竭形式是急性低氧性呼吸衰竭，临床上四分之三的ICU患者表现为急性呼吸窘迫综合征（ARDS）。无创呼吸支持模式的使用频率越来越高，因为它们有可能减少对插管的需求。确定最佳的患者选择和插管时间仍然是一个挑战。COVID-19机械通气患者的管理与非COVID-19 ARDS的管理基本一致。器官衰竭是常见的，预示着预后不良。在大流行期间，死亡率有所改善，这可能是由于对疾病的熟悉程度提高、数据驱动的药理学以及对循证重症监护的依从性提高。
The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges in critical care medicine, including extreme demand for intensive care unit (ICU) resources and rapidly evolving understanding of a novel disease. Up to one-third of hospitalized patients with COVID-19 experience critical illness. The most common form of organ failure in COVID-19 critical illness is acute hypoxemic respiratory failure, which clinically presents as acute respiratory distress syndrome (ARDS) in three-quarters of ICU patients. Noninvasive respiratory support modalities are being used with increasing frequency given their potential to reduce the need for intubation. Determining optimal patient selection for and timing of intubation remains a challenge. Management of mechanically ventilated patients with COVID-19 largely mirrors that of non-COVID-19 ARDS. Organ failure is common and portends a poor prognosis. Mortality rates have improved over the course of the pandemic, likely owing to increasing disease familiarity, data-driven pharmacologics, and improved adherence to evidence-based critical care.
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影响因子：
2.5
作者：
Divo, Miguel J.;Oberg, Catherine L.;Folch, Erik E.
通讯作者：
Folch, Erik E.
影响因子：
64.8
作者：
通讯作者：
--
DOI：
10.1016/s0140-6736(20)32008-0
发表时间：
2020-10-10
期刊：
Lancet (London, England)
影响因子：
--
作者：
Barbaro RP;MacLaren G;Boonstra PS;Iwashyna TJ;Slutsky AS;Fan E;Bartlett RH;Tonna JE;Hyslop R;Fanning JJ;Rycus PT;Hyer SJ;Anders MM;Agerstrand CL;Hryniewicz K;Diaz R;Lorusso R;Combes A;Brodie D;Extracorporeal Life Support Organization
通讯作者：
Extracorporeal Life Support Organization
影响因子：
8.8
作者：
Devlin, John W.;Skrobik, Yoanna;Alhazzani, Waleed
通讯作者：
Alhazzani, Waleed
影响因子：
8.1
作者：
Bonnet N;Martin O;Boubaya M;Levy V;Ebstein N;Karoubi P;Tandjaoui-Lambiotte Y;Van Der Meersch G;Oziel J;Soulie M;Ghalayini M;Winchenne A;Zahar JR;Ahmed P;Gaudry S;Cohen Y
通讯作者：
Cohen Y