Mapping and correction of vascular hemodynamic latency in the BOLD signal.
Mapping and correction of vascular hemodynamic latency in the BOLD signal.
复制标题
DOI:
10.1016/j.neuroimage.2008.06.030
复制
发表时间:
2008-10-15
期刊:
影响因子:
5.7
通讯作者:
Glover, Gary H.
中科院分区:
文献类型:
--
作者:
Chang, Catie;Thomason, Moriah E.;Glover, Gary H.
Correlation and causality metrics can be applied to blood-oxygen level dependent (BOLD) signal time series in order to infer neural synchrony and directions of information flow from fMRI data. However, the BOLD signal reflects both the underlying neural activity and the vascular response, the latter of which is governed by local vasomotor physiology. The presence of potential vascular latency differences thus poses a confound in the detection of neural synchrony as well as inferences about the causality of neural processes. In the present study, we investigate the use of a breath holding (BH) task for characterizing and correcting for voxel-wise neurovascular latency differences across the whole brain. We demonstrate that BH yields reliable measurements of relative timing differences between voxels, and further show that a BH-derived correction can impact both functional connectivity maps of the resting-state default-mode network and activation maps of an event-related working memory (WM) task.
登录
查看更多内容
影响因子:
5.7
作者:
Daselaar, SM;Prince, SE;Cabeza, R
通讯作者:
Cabeza, R
影响因子:
3.2
作者:
Greicius, MD;Menon, V
通讯作者:
Menon, V
影响因子:
5.7
作者:
Friston, KJ;Fletcher, P;Turner, R
通讯作者:
Turner, R
影响因子:
5.7
作者:
Cohen, ER;Rostrup, E;Kim, SG
通讯作者:
Kim, SG
DOI:
10.1073/pnas.95.4.1834
发表时间:
1998-02-17
影响因子:
11.1
作者:
Davis, TL;Kwong, KK;Rosen, BR
通讯作者:
Rosen, BR