Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers.
Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers.
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饮食锌来源会影响年轻肉鸡的肠形态和氧化应激。
DOI：
10.3382/ps/pez525
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发表时间：
2020-01
期刊：
影响因子：
4.4
通讯作者：
Ducatelle R
中科院分区：
文献类型：
--
作者：
De Grande A;Leleu S;Delezie E;Rapp C;De Smet S;Goossens E;Haesebrouck F;Van Immerseel F;Ducatelle R
锌是所有生命形式的必需营养微量元素，因为它在许多生物过程中起着重要作用。在家禽中，锌是通过饲料中补充提供的，主要是氧化锌或硫酸锌。或者，锌可以作为有机源补充，其特征在于使用有机配体结合锌，并且具有比无机锌源更高的生物利用度，所述有机配体可以是氨基酸、肽或蛋白质。直接比较无机锌源与有机锌源对肉鸡生产性能和肠道健康影响的研究数量有限。因此，进行消化率和性能研究以评估和比较氨基酸络合锌源与无机锌源对肠道健康的影响。试验分为2个处理：在小麦-黑麦日粮中添加锌氨基酸复合物或硫酸锌，锌含量为60 ppm，每个处理10个重复（每栏34只肉鸡）。测量对性能、肠道形态、微生物群组成和氧化应激的影响。与补充硫酸锌相比，补充锌氨基酸复合物提高了锌的消化率系数。与补充硫酸锌的鸡相比，补充锌氨基酸络合物的肉鸡在起始阶段具有显著较低的饲料转化率。在第10天和第28天，在补充锌氨基酸复合物的肉鸡中观察到显著更高的绒毛长度。补充锌氨基酸复合物导致属于变形菌门的几个属的丰度降低。血浆丙二醛水平和谷胱甘肽过氧化物酶活性表明，在肉鸡补充锌氨基酸络合物的氧化状态改善。总之，在饲料中提供的锌作为氨基酸复合物更容易吸收，可能赋予一个保护作用的绒毛上皮细胞在启动阶段。
Zinc is an essential nutritional trace element for all forms of life as it plays an important role in numerous biological processes. In poultry, zinc is provided by in-feed supplementation, mainly as zinc oxide or zinc sulfate. Alternatively zinc can be supplemented as organic sources, which are characterized by using an organic ligand that may be an amino acid, peptide, or protein to bind zinc and have a higher bioavailability than inorganic zinc sources. There are limited number of studies directly comparing the effects of inorganic vs. organic zinc sources on performance and intestinal health in broilers. Therefore, a digestibility and a performance study were conducted to evaluate and compare the effect of an amino acid-complexed zinc source vs. an inorganic zinc source on intestinal health. The experiment consisted of 2 treatments: either a zinc amino acid complex or zinc sulfate was added to a wheat–rye based diet at 60 ppm Zn, with 10 replicates (34 broilers per pen) per treatment. Effects on performance, intestinal morphology, microbiota composition, and oxidative stress were measured. Supplementing zinc amino acid complexes improved the zinc digestibility coefficient as compared to supplementation with zinc sulfate. Broilers supplemented with zinc amino acid complexes had a significantly lower feed conversion ratio in the starter phase compared to birds supplemented with zinc sulfate. A significantly higher villus length was observed in broilers supplemented with zinc amino acid complexes at days 10 and 28. Supplementation with zinc amino acid complexes resulted in a decreased abundance of several genera belonging to the phylum of Proteobacteria. Plasma malondialdehyde levels and glutathione peroxidase activity showed an improved oxidative status in broilers supplemented with zinc amino acid complexes. In conclusion, zinc supplied in feed as amino acid complex is more readily absorbed, potentially conferring a protective effect on villus epithelial cells in the starter phase.
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