ARABIDOPSIS THALIANA HOMEOBOX GENE 1 controls plant architecture by locally restricting environmental responses.
ARABIDOPSIS THALIANA HOMEOBOX GENE 1 controls plant architecture by locally restricting environmental responses.
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拟南芥Homeobox基因1通过局部限制环境反应来控制植物结构。
DOI：
10.1073/pnas.2018615118
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发表时间：
2021-04-27
影响因子：
11.1
通讯作者：
Sablowski R
中科院分区：
文献类型：
--
作者：
Ejaz M;Bencivenga S;Tavares R;Bush M;Sablowski R
植物生物学中的一个主要问题是，植物是如何通过内部遗传程序--例如，形成叶和茎之间边界的程序--与环境信号(如在阴凉处诱导茎伸长的光质)之间的相互作用来塑造植物的。在许多植物中，茎的生长在营养阶段受到抑制，导致紧凑的叶片轮生，称为莲座丛。我们发现拟南芥的玫瑰花结习性是由一个参与器官边界形成的基因和赤霉素激素信号所赋予的，这两个基因都拮抗调节器官生长对光的反应的基因。通过这种方式，一种常见的植物结构类型是由于对环境响应生长的局部抑制造成的。植物生长的多样性和环境可塑性源于重复单元的变化，如由叶、腋芽和节间组成的基本枝条单位。节间伸长受发育和环境条件的调节，如光质，但对内部和环境信号的整合知之甚少。在这里，我们证明了拟南芥的压缩玫瑰生长习性是由器官边界基因拟南芥同源盒基因1(ATH1)和赤霉素信号转导基因della的趋同活性维持的。ATH1和Della功能的共同丧失激活了营养生长期的茎发育，使茎的生长习性从丛生变为茎生。染色质免疫沉淀高通量测序和遗传分析表明，ATH1和Della基因抑制子GA1-3(RGA)在光反应的调节上是一致的，包括光敏色素相互作用因子(PIF)途径，并表明ATH1的部分输入是通过直接激活叶柄上的叶片(BOP1和BOP2)基因来介导的，其产物破坏了PIF蛋白的稳定。我们的结论是，器官模式基因与激素信号融合在一起，在空间上限制了环境反应，并建立了广泛类型的植物结构。
A major issue in plant biology is how plants are shaped by the interaction between internal genetic programs—for example, those that form boundaries between leaves and the stem—and environmental signals such as light quality, which induces stem elongation in shade conditions. In many plant species, stem growth is suppressed during the vegetative phase, resulting in a compact whorl of leaves called a rosette. We show that the rosette habit of Arabidopsis is conferred by a gene involved in organ boundary formation, together with gibberellin hormone signaling, both of which antagonize genes that mediate organ growth in response to light. In this way, a common type of plant architecture results from localized inhibition of environmentally responsive growth. The diversity and environmental plasticity of plant growth results from variations of repetitive modules, such as the basic shoot units made of a leaf, axillary bud, and internode. Internode elongation is regulated both developmentally and in response to environmental conditions, such as light quality, but the integration of internal and environmental signals is poorly understood. Here, we show that the compressed rosette growth habit of Arabidopsis is maintained by the convergent activities of the organ boundary gene ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1) and of the gibberellin-signaling DELLA genes. Combined loss of ATH1 and DELLA function activated stem development during the vegetative phase and changed the growth habit from rosette to caulescent. Chromatin immunoprecipitation high-throughput sequencing and genetic analysis indicated that ATH1 and the DELLA gene REPRESSOR OF GA1-3 (RGA) converge on the regulation of light responses, including the PHYTOCHROME INTERACTING FACTORS (PIF) pathway, and showed that the ATH1 input is mediated in part by direct activation of BLADE ON PETIOLE (BOP1 and BOP2) genes, whose products destabilize PIF proteins. We conclude that an organ-patterning gene converges with hormone signaling to spatially restrict environmental responses and establish a widespread type of plant architecture.
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影响因子：
14.9
作者：
Cole, M;Nolte, C;Werr, W
通讯作者：
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影响因子：
10.5
作者：
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18
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DOI：
10.1073/pnas.93.8.3530
发表时间：
1996-04-16
影响因子：
11.1
作者：
Carabelli, M;Morelli, G;Ruberti, I
通讯作者：
Ruberti, I
模因套件：用于发现和搜索的工具。
影响因子：
14.9
作者：
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通讯作者：
Noble WS