B81 Bone Vibrator-Induced Vestibular-Evoked Myogenic Potentials: Normal Values and the Effect of Age.
B81 Bone Vibrator-Induced Vestibular-Evoked Myogenic Potentials: Normal Values and the Effect of Age.
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DOI：
10.3389/fneur.2022.881682
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发表时间：
2022
影响因子：
3.4
通讯作者：
中科院分区：
文献类型：
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目的确定B81骨振仪诱发的颈前庭诱发肌源性电位（B81-cVEMPs）和眼前庭诱发肌源性电位（B81-oVEMPs）的正常值，并探讨年龄对这两种电位的影响。70名健康受试者，根据他们的年龄分为7组，参加了这项研究。4-9岁、10-19岁、20-29岁、30-39岁、40- 4 - 9岁、50-59岁和60-70岁的参与者分别被分为I-VII组。记录各组大鼠B81-cVEMP和B81-oVEMP。组I-VII的B81-cVEMP应答率分别为100、100、100、100、95、95和75%，仅组I-VI和组VII之间存在显著差异（p = 0.047，p < 0.05）。组I-VII的B81-oVEMP应答率分别为100、100、100、100、70、65和40%，仅组I-IV和组V-VII之间存在显著差异（p = 0.020，p = 0.008，p = 0.000; p < 0.05）。B81-cVEMP阈值、P13和N23潜伏期与年龄呈正相关（r = 0.756，p = 0.000; r = 0.357，p = 0.003; r = 0.316，p = 0.009; p < 0.05）。原始振幅和校正振幅与年龄呈负相关（r =-0.641，p = 0.000; r =-0.609，p = 0.000，p < 0.05）。对于B81-oVEMP，校正幅度与年龄呈负相关（r =-0.638，p = 0.000，p<0.05），但阈值和N10潜伏期与年龄呈正相关（r = 0.768，p = 0.000; r = 0.334，p = 0.009，p < 0.05）。此外，B81-cVEMP和B81-oVEMP的耳间不对称率与年龄无显著相关性。随着年龄的增长，B81-cVEMP反应率降低，阈值升高，P13和N23潜伏期延长，原始振幅和校正振幅降低。随年龄增长，B81-oVEMP反应率和校正波幅降低，阈值升高，N10潜伏期延长。这些变化可能是由于前庭系统随着年龄的增长发生了形态和功能的变化。因此，我们建议在评价前庭疾病患者的VEMP结果时，根据不同年龄组建立不同的参考值。
To define the normal values and examine the influence of aging on B81 bone vibrator-induced cervical vestibular-evoked myogenic potentials (B81-cVEMPs) and ocular vestibular-evoked myogenic potentials (B81-oVEMPs). Seventy healthy subjects, divided into seven groups according to their ages, were enrolled in this study. The 4–9-, 10–19-, 20–29-, 30–39-, 40–49-, 50–59-, and 60–70-year-old participants were divided into groups I–VII, respectively. B81-cVEMP and B81-oVEMP were recorded in each group. The B81-cVEMP response rates for groups I–VII were 100, 100, 100, 100, 95, 95, and 75%, respectively, with significant differences only between groups I–VI and group VII (p = 0.047, p < 0.05). The B81-oVEMP response rates for groups I–VII were 100, 100, 100, 100, 70, 65, and 40%, respectively, with significant differences only between groups I–IV and groups V–VII (p = 0.020, p = 0.008, p = 0.000; p < 0.05). The threshold, P13, and N23 latencies of B81-cVEMP positively correlated with age (r = 0.756, p = 0.000; r = 0.357, p = 0.003; r = 0.316, p = 0.009; p < 0.05). The raw amplitudes and corrected amplitudes negatively correlated with age (r = −0.641, p = 0.000; r = −0.609, p = 0.000, p < 0.05). For B81-oVEMP, the corrected amplitudes negatively correlated with age (r = −0.638, p = 0.000, p<0.05), but the threshold and N10 latency positively correlated with age (r = 0.768, p = 0.000; r = 0.334, p = 0.009, p < 0.05). Moreover, the interaural asymmetry ratio did not significantly correlate with age for B81-cVEMP and B81-oVEMP. As age increased, the B81-cVEMP response rate decreased, the thresholds increased, P13 and N23 latencies were prolonged, and the raw amplitude and corrected amplitude decreased. The B81-oVEMP response rate and corrected amplitude decreased, the thresholds increased, and N10 latency was prolonged with age. These changes are probably due to the occurrence of morphological and functional changes in the vestibular system with aging. Therefore, we suggest establishing different reference values according to different age groups when evaluating the VEMP results in patients with vestibular diseases.
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影响因子：
3.7
作者：
Patterson JN;Rodriguez AI;Gordon KR;Honaker JA;Janky KL
通讯作者：
Janky KL
DOI：
10.1097/mao.0b013e318271c32a
发表时间：
2013-01
期刊：
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
影响因子：
--
作者：
Janky KL;Nguyen KD;Welgampola M;Zuniga MG;Carey JP
通讯作者：
Carey JP
影响因子：
2.7
作者：
Jansson, Karl-Johan Freden;Hakansson, Bo;Tengstrand, Tomas
通讯作者：
Tengstrand, Tomas
影响因子：
3.7
作者：
Romero, Daniel J.;Piker, Erin G.;Clinard, Christopher
通讯作者：
Clinard, Christopher
影响因子：
3.7
作者：
McCaslin, Devin L.;Jacobson, Gary P.;DeLong, Andrew P.
通讯作者：
DeLong, Andrew P.