Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.
Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.
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DOI：
10.1038/npjsba.2016.11
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发表时间：
2016
影响因子：
4
通讯作者：
Hohmann S
中科院分区：
文献类型：
--
作者：
Cvijovic M;Höfer T;Aćimović J;Alberghina L;Almaas E;Besozzi D;Blomberg A;Bretschneider T;Cascante M;Collin O;de Atauri P;Depner C;Dickinson R;Dobrzynski M;Fleck C;Garcia-Ojalvo J;Gonze D;Hahn J;Hess HM;Hollmann S;Krantz M;Kummer U;Lundh T;Martial G;Dos Santos VM;Mauer-Oberthür A;Regierer B;Skene B;Stalidzans E;Stelling J;Teusink B;Workman CT;Hohmann S
系统生物学是生物学和医学的一种方法，有可能导致更好地理解生物特性如何从基因，蛋白质，分子，细胞和生物体的相互作用中产生。该方法旨在阐明这些相互作用如何通过使用实验数据，数学模型和计算机模拟来控制生物功能。由于系统生物学本质上是多学科的，这一领域的教育遇到了许多障碍，包括部门障碍，当地所有所需的专业知识，适当的教材和示例课程的可用性。由于本科水平的大学教育传统上是建立在学科学位的基础上，我们认为实施系统生物学教育的最有效方法是在硕士水平，因为它提供了一个更灵活的框架。我们的专家团队和系统生物学教育的积极执行者在这里建议（i）学生应该在系统生物学硕士课程中获得的技能的定义，（ii）可能的基础教育课程具有灵活性，以适应不同的应用领域和当地的研究优势，（iii）对接受这种教育的学生可能的职业道路的描述，（iv）应改善招收学生参加这类方案的条件，以及（v）在教育专业人员中传播协作和优秀成果的机制。随着工业界对在其领域应用系统生物学方法的兴趣日益浓厚，学术界和工业界之间需要采取协调一致的行动来建立这种专业知识。在这里，我们介绍了欧洲的情况和专业知识，我们讨论的大多数挑战都是普遍的，预计我们的建议将在国际上有用。我们认为，任何系统生物学教育的首要目标之一应该是学生的措辞和沟通研究问题的能力，以这样的方式，他们可以通过实验和建模的整合来解决，以及沟通和合作富有成效地跨越不同的实验和理论学科的研究和发展。
Systems Biology is an approach to biology and medicine that has the potential to lead to a better understanding of how biological properties emerge from the interaction of genes, proteins, molecules, cells and organisms. The approach aims at elucidating how these interactions govern biological function by employing experimental data, mathematical models and computational simulations. As Systems Biology is inherently multidisciplinary, education within this field meets numerous hurdles including departmental barriers, availability of all required expertise locally, appropriate teaching material and example curricula. As university education at the Bachelor’s level is traditionally built upon disciplinary degrees, we believe that the most effective way to implement education in Systems Biology would be at the Master’s level, as it offers a more flexible framework. Our team of experts and active performers of Systems Biology education suggest here (i) a definition of the skills that students should acquire within a Master’s programme in Systems Biology, (ii) a possible basic educational curriculum with flexibility to adjust to different application areas and local research strengths, (iii) a description of possible career paths for students who undergo such an education, (iv) conditions that should improve the recruitment of students to such programmes and (v) mechanisms for collaboration and excellence spreading among education professionals. With the growing interest of industry in applying Systems Biology approaches in their fields, a concerted action between academia and industry is needed to build this expertise. Here we present a reflection of the European situation and expertise, where most of the challenges we discuss are universal, anticipating that our suggestions will be useful internationally. We believe that one of the overriding goals of any Systems Biology education should be a student’s ability to phrase and communicate research questions in such a manner that they can be solved by the integration of experiments and modelling, as well as to communicate and collaborate productively across different experimental and theoretical disciplines in research and development.
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影响因子：
7.4
作者：
Cascante M;de Atauri P;Gomez-Cabrero D;Wagner P;Centelles JJ;Marin S;Cano I;Velickovski F;Marin de Mas I;Maier D;Roca J;Sabatier P
通讯作者：
Sabatier P
影响因子：
4.3
作者：
Searls DB
通讯作者：
Searls DB
影响因子：
9.8
作者：
Cira NJ;Chung AM;Denisin AK;Rensi S;Sanchez GN;Quake SR;Riedel-Kruse IH
通讯作者：
Riedel-Kruse IH
影响因子：
9.5
作者：
Abeln, Sanne;Molenaar, Douwe;Heringa, Jaap
通讯作者：
Heringa, Jaap
影响因子：
56.9
作者：
Haak, David C.;HilleRisLambers, Janneke;Freeman, Scott
通讯作者：
Freeman, Scott