How Reaction-Diffusion PDEs Approximate the Large-Population Limit of Stochastic Particle Models
How Reaction-Diffusion PDEs Approximate the Large-Population Limit of Stochastic Particle Models
复制标题
反应扩散偏微分方程如何逼近随机粒子模型的大总体极限
DOI:
10.1137/20m1365429
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发表时间:
2021
影响因子:
1.9
通讯作者:
Spiliopoulos, Konstantinos
中科院分区:
文献类型:
--
作者:
Isaacson, Samuel A.;Ma, Jingwei;Spiliopoulos, Konstantinos
Reaction-diffusion PDEs and particle-based stochastic reaction-diffusion (PBSRD) models are commonly used approaches for modeling the spatial dynamics of chemical and biological systems. Standard reaction-diffusion PDE models ignore the underlying stochasticity of spatial transport and reactions and are often described as appropriate in regimes where there are large numbers of particles in a system. Recent studies have proven the rigorous large-population limit of PBSRD models, showing the resulting mean-field models (MFMs) correspond to nonlocal systems of partial-integro differential equations. In this work we explore the rigorous relationship between standard reaction-diffusion PDE models and the derived MFM. We prove that the former can be interpreted as an asymptotic approximation to the later in the limit that bimolecular reaction kernels are short-range and averaging. As the reactive interaction length scale approaches zero, we prove the MFMs converge at second order to standard reaction-diffusion PDE models. In proving this result we also establish local well-posedness of the MFM model in time for general systems and global well-posedness for specific reaction systems and kernels. Finally, we illustrate the agreement and disagreement between the MFM, SM, and underlying particle model for several numerical examples.
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影响因子:
4.3
作者:
Muñoz-García J;Neufeld Z;Kholodenko BN
通讯作者:
Kholodenko BN
DOI:
10.1137/20m1352739
发表时间:
2020
期刊:
Multiscale Model. Simul.
影响因子:
--
作者:
Margarita Kostré;C. Schütte;Frank No'e;M. D. Razo
通讯作者:
M. D. Razo
DOI:
10.1137/18m1178839
发表时间:
2018-04
期刊:
SIAM J. Math. Anal.
影响因子:
--
作者:
Joachim Crevat;Grégory Faye;F. Filbet
通讯作者:
Joachim Crevat;Grégory Faye;F. Filbet
DOI:
--
发表时间:
1967
期刊:
影响因子:
--
作者:
E. Teramoto;N. Shigesada
通讯作者:
N. Shigesada
影响因子:
4.3
作者:
Swadesh Pal;S. Ghorai;M. Banerjee
通讯作者:
Swadesh Pal;S. Ghorai;M. Banerjee