Serum vitamin D, calcium, and zinc levels in patients with COVID-19.
Serum vitamin D, calcium, and zinc levels in patients with COVID-19.
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DOI：
10.1016/j.clnesp.2021.03.040
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发表时间：
2021-06
影响因子：
3
通讯作者：
Marzieh N
中科院分区：
文献类型：
--
作者：
Elham AS;Azam K;Azam J;Mostafa L;Nasrin B;Marzieh N
COVID-19是全球公共卫生问题。由于尚未发现标准治疗方法，因此具有抗氧化剂，免疫调节剂和抗菌剂作用的几种矿物质和维生素足以对抗疾病的免疫反应。本研究评估了COVID-19患者的血清维生素D、钙和锌水平。这项研究是一项于2020年5月对93名在Shoushtar市医院住院的COVID-19患者和186名没有COVID-19症状的健康受试者进行的病例对照研究。收集血清维生素D、钙和锌水平，并通过SPSS 18使用相关系数和独立t检验进行分析。维生素D水平在病例组和对照组之间有显著差异（p = 0.008）。两组血清钙、锌水平差异有统计学意义（P < 0.001）。研究结果显示，COVID-19患者的血清锌、钙和维生素D水平低于对照组。补充这些营养素是一种安全且低成本的措施，有助于科普因感染COVID-19病毒而对这些营养素需求增加的风险。
COVID-19 is a global public health concern. As no standard treatment has been found for it yet, several minerals and vitamins with antioxidants, immunomodulators, and antimicrobials roles can be sufficient for the immune response against the disease. The present study evaluates the serum vitamin D, calcium, and Zinc levels in patients with COVID-19. This research is a case–control study performed in May 2020 on 93 patients with COVID-19 hospitalized in a Shoushtar city hospital and on 186 healthy subjects with no symptoms of COVID-19. The serum vitamin D, calcium, and zinc levels were collected and analyzed using correlation coefficient and independent t-test via SPSS 18. Vitamin D levels had a significant difference between the case and control groups (p = 0.008). Serum calcium and serum zinc levels also had statistically significant differences between the two groups (p < 0.001). The research results showed that serum zinc, calcium, and vitamin D levels in COVID-19 patients are lower than in the control group. The supplementation with such nutrients is a safe and low-cost measure that can help cope with the increased demand for these nutrients in risk of acquiring the COVID-19 virus.
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