A dominance analysis of subjective cognitive complaint comorbidities in former professional football players with and without mild cognitive impairment.
A dominance analysis of subjective cognitive complaint comorbidities in former professional football players with and without mild cognitive impairment.
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DOI：
10.1017/s135561772200056x
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发表时间：
2023-07
影响因子：
2.6
通讯作者：
McCrea, Michael A.
中科院分区：
文献类型：
--
作者：
Brett, Benjamin L.;Kerr, Zachary Yukio;Chandran, Avinash;Walton, Samuel;Aggarwal, Neelum T.;Gifford, Katherine;Mannix, Rebekah;DeFreese, J. D.;Echemendia, Ruben J.;Guskiewicz, Kevin M.;Meehan, William P.;McCrea, Michael A.
主观认知困难（SCD）与老年人和前接触性运动员中常见的因素相关，无论客观认知能力下降如何。我们调查了这些因素对前美国国家橄榄球联盟（NFL）运动员中有和没有轻度认知障碍（MCI）诊断的SCD的相对贡献。前NFL球员（n = 907）年龄≥ 50岁（平均= 64.7 ± 8.9），有（n = 165）和没有（n = 742）MCI诊断完成健康问卷。多变量回归和优势分析确定了SCD因素对SCD的相对重要性：1）抑郁，2）焦虑，3）睡眠障碍，4）疼痛干扰，5）参与社会角色和活动的能力，6）压力相关事件，7）疲劳，8）脑震荡史，9）教育。SCD结局包括神经生活质量、预防行为控制障碍和PROMIS认知功能。Fisher z变换比较了MCI和非MCI组中SCD的共病促成因素。在MCI组和非MCI组中，焦虑在大多数共病因素中占绝对优势。疲劳对大多数共病因素也表现出完全的优势，尽管它在MCI组中的影响不太强烈（一般优势）。MCI组和非MCI组之间共病因素对SCD评分的平均方差贡献无统计学差异（Z-统计量<1.96，ps>.05）。焦虑和疲劳是前职业足球运动员在各种临床表现组合（共病因素的不同组合）中与SCD相关的最强有力的因素，无论记录的认知障碍如何。自我报告的缺陷可能是不太可靠的检测客观损害在这些因素的存在下，与多维评估是理想的。
Subjective cognitive difficulties (SCDs) are associated with factors commonly reported in older adults and former contact sport athletes, regardless of objective cognitive decline. We investigated the relative contribution of these factors to SCD in former National Football League (NFL)-players with and without a diagnosis of mild cognitive impairment (MCI). Former NFL players (n = 907) aged ≥ 50 years (mean = 64.7 ± 8.9), with (n = 165) and without (n = 742) a diagnosis of MCI completed health questionnaires. Multivariable regression and dominance analyses determined the relative importance of SCD factors on SCD: 1) depression, 2) anxiety, 3) sleep disturbance, 4) pain interference, 5) ability to participate in social roles and activities, 6) stress-related events, 7) fatigue, 8) concussion history, and 9) education. SCD outcomes included Neuro-QoL Emotional-Behavioral Dyscontrol and the PROMIS Cognitive Function. Fisher’s z-transformation compared comorbid contributing factors to SCD across MCI and non-MCI groups. Complete dominance of anxiety was established over most comorbid factors across the MCI and non-MCI groups. Fatigue also exhibited complete dominance over most comorbid factors, though its influence in the MCI group was less robust (general dominance). Average contributions to variance accounted for by comorbid factors to ratings of SCD across MCI and non-MCI groups did not statistically differ (Z-statistics <1.96, ps>.05). Anxiety and fatigue are the most robust factors associated with SCD in former professional football players across various combinations of clinical presentations (different combinations of comorbid factors), regardless of documented cognitive impairment. Self-reported deficits may be less reliable in detecting objective impairment in the presence of these factors, with multidimensional assessment being ideal.
影响因子：
4.3
作者：
Thackeray A;Marcus RL;Yu L;McCracken P;Cardell B;Hanmer J
通讯作者：
Hanmer J