Mucus.
Mucus.
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粘液。
DOI：
10.1016/j.cub.2021.06.093
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发表时间：
2021-08-09
期刊：
影响因子：
--
通讯作者：
Ribbeck K
中科院分区：
文献类型：
--
作者：
McShane A;Bath J;Jaramillo AM;Ridley C;Walsh AA;Evans CM;Thornton DJ;Ribbeck K
Mucus is a slimy hydrogel that lines the mucosal surfaces in our body, including the intestines, stomach, eyes, lungs and urogenital tract. This glycoprotein-rich network is truly the jack of all trades. As a barrier, it lubricates surfaces, protects our cells from physical stress, and selectively allows the passage of nutrients while clearing out pathogens and debris. As a home to our microbiota, it supports a level of microbial diversity that is unattainable with most culture methods. As a reservoir of complex carbohydrate structures called glycans, it plays critical roles in controlling cell adhesion and signaling, and it alters the behavior and spatial distribution of microbes. On top of all this, mucus regulates the passage of sperm during fertilization, heals wounds, helps us smell, and prevents the stomach from digesting itself, to name just a few of its functions. Given these impressive features, it is no wonder that mucus crosses boundaries of species and kingdoms — mucus gels are made by organisms ranging from the simplest metazoans to corals, snails, fish, and frogs. It is also no surprise that mucus is exploited in everyday applications, including foods, cosmetics, and other products relevant to medicine and industry.
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影响因子：
16.1
作者：
Lai, Samuel K.;Wang, Ying-Ying;Hanes, Justin
通讯作者：
Hanes, Justin
影响因子：
15.3
作者：
Campbell, Laura;Hepworth, Matthew R.;Grencis, Richard K.
通讯作者：
Grencis, Richard K.
DOI：
10.1073/pnas.0705984104
发表时间：
2007-10-09
影响因子：
11.1
作者：
Lang, Tiange;Hansson, Gunnar C.;Samuelsson, Tore
通讯作者：
Samuelsson, Tore
影响因子：
5.4
作者：
Verdugo, Pedro
通讯作者：
Verdugo, Pedro
影响因子：
78.5
作者：
Kufe, Donald W.
通讯作者：
Kufe, Donald W.