Calculation of internal dose from ingested soil-derived uranium in humans: Application of a new method
Calculation of internal dose from ingested soil-derived uranium in humans: Application of a new method
复制标题
人体摄入土壤衍生铀的体内剂量计算：新方法的应用
DOI：
10.1007/s00411-015-0602-9
复制
发表时间：
2015
影响因子：
1.7
通讯作者：
Rühm W
中科院分区：
文献类型：
--
作者：
Träber SC;Höllriegl V;Nebelung K;Michalke B;Rühm W
本研究的目的是确定人体在摄入高度受铀污染的土壤后的体内剂量。因此，进行了铀在两种土壤中的生物可及性的体外溶解试验。在此基础上，利用最近发表的方法对相应的生物利用度进行了评估。最后，将这些生物利用度数据与铀的生物动力学模型一起用于评估假设但现实情景下的内部剂量，该情景的特征是在1年内每天摄入10毫克土壤。调查的土壤样本来自德国的两个前铀矿场，其238U浓度分别约为460和550 mg/kg。这些土壤中238U的生物有效性分别为0.18和0.28%(几何平均值)，2.5个百分位数分别为0.02和0.03%，97.5个百分位数分别为1.48和2.34%。假设情景的相应计算年承诺有效剂量为0.4和0.6微西弗(Gm)，第2.5个百分位数分别为0.2和0.3微西弗，97.5个百分位数为1.6和3.0微西弗。这些年承诺有效剂量与食物和饮用水摄入天然铀的剂量相似，估计为0.5亿微西弗。根据目前的实验数据和选定的摄取情景，所调查的土壤--尽管受到高度铀污染--预计不会对人类构成与辐射有关的任何重大健康威胁。
The aim of the present study was to determine the internal dose in humans after the ingestion of soil highly contaminated with uranium. Therefore, an in vitro solubility assay was performed to estimate the bioaccessibility of uranium for two types of soil. Based on the results, the corresponding bioavailabilities were assessed by using a recently published method. Finally, these bioavailability data were used together with the biokinetic model of uranium to assess the internal doses for a hypothetical but realistic scenario characterized by a daily ingestion of 10 mg of soil over 1 year. The investigated soil samples were from two former uranium mining sites of Germany with238U concentrations of about 460 and 550 mg/kg. For these soils, the bioavailabilities of238U were quantified as 0.18 and 0.28 % (geometric mean) with 2.5th percentiles of 0.02 and 0.03 % and 97.5th percentiles of 1.48 and 2.34 %, respectively. The corresponding calculated annual committed effective doses for the assumed scenario were 0.4 and 0.6 µSv (GM) with 2.5th percentiles of 0.2 and 0.3 µSv and 97.5th percentiles of 1.6 and 3.0 µSv, respectively. These annual committed effective doses are similar to those from natural uranium intake by food and drinking water, which is estimated to be 0.5 µSv. Based on the present experimental data and the selected ingestion scenario, the investigated soils—although highly contaminated with uranium—are not expected to pose any major health risk to humans related to radiation.
登录
查看更多内容
公众因摄入放射性核素而受到的年龄相关剂量：第 4 部分吸入剂量系数
影响因子：
--
作者：
Icrp
通讯作者：
Icrp
合成肠道液中愈合土中的铀和钍的溶解度：用于剂量评估的案例研究。
影响因子：
9.8
作者：
V. Höllriegl;Wei Bo Li;K. Leopold;U. Gerstmann;U. Oeh
通讯作者：
U. Oeh
影响因子：
5.8
作者：
Francesca Langella;A. Grawunder;Romy Stark;Aileen Weist;D. Merten;Götz Haferburg;G. Büchel;E. Kothe
通讯作者：
Francesca Langella;A. Grawunder;Romy Stark;Aileen Weist;D. Merten;Götz Haferburg;G. Büchel;E. Kothe
空气中的灰尘和食土直接暴露土壤对人类健康的影响
影响因子：
--
作者：
David B. Sing;C. Sing
通讯作者：
C. Sing
加拿大安大略省霍普港土壤样品中铀的生物可接近性。
影响因子：
11.4
作者：
S. Jovanovic;P. Pan;Larry Wong
通讯作者：
Larry Wong