Neurons in primary motor cortex engaged during action observation.
Neurons in primary motor cortex engaged during action observation.
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DOI：
10.1111/j.1460-9568.2009.07067.x
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发表时间：
2010-01
期刊：
影响因子：
--
通讯作者：
Donoghue J
中科院分区：
文献类型：
--
作者：
Dushanova J;Donoghue J
高级皮层区域的神经元在观察动作的过程中似乎变得活跃起来，要么是通过镜像观察到的动作（称为镜像神经元），要么是通过引发对观察到的运动动作的心理预演。我们报告存在的神经元在初级运动皮层（MI）响应所看到的行动，该地区通常被认为是发起和指导运动性能。在猴子执行或观察一个很好的学习步骤跟踪任务的多电极记录显示，大约一半的MI神经元，活跃时，猴子执行的任务，也活跃时，他们观察到的行动正在由一个人。这些“视图”神经元在空间上与“做”神经元混合，仅在运动表现期间活跃。同时记录，“视图”神经元包括两组：1038%的保持相同的首选方向（PD）和时间在性能和观看，而其余的（62%）改变他们的PD和时间滞后在观看性能相比。尽管如此，观看期间的种群活动足以预测随着动作展开而观看的运动的方向和轨迹，尽管不如表演期间准确。“视图”神经元变得不那么活跃，并且在只查看任务的子组件时包含更差的动作表示。因此，当在其他人身上观察时，MI“视图”神经元似乎反映了学习运动的各个方面，并形成了一组广泛参与的皮层区域的一部分，这些区域通常对学习行为做出反应。这些研究结果表明，观看一个学到的动作elimanate重放的MI活动的方面需要执行所观察到的行动，并可以另外反映相关的理解，学习或心理排练行动的处理。
Neurons in higher cortical areas appear to become active during action observation, either by mirroring observed actions (termed mirror neurons) or by eliciting mental rehearsal of observed motor acts. We report the existence of neurons in primary motor cortex (MI) responding to viewed actions, an area generally considered to initiate and guide movement performance. Multielectrode recordings in monkeys performing or observing a well-learned step tracking task showed that approximately half of MI neurons, active when monkeys performed the task, were also active when they observed the action being performed by a human. These ‘view’ neurons were spatially intermingled with ‘do’ neurons, active only during movement performance. Simultaneously recorded, ‘view’ neurons comprised two groups: ∼38% retained the same preferred direction (PD) and timing during performance and viewing, while the remainder (62%) changed their PDs and time lag during viewing compared with performance. Nevertheless, population activity during viewing was sufficient to predict the direction and trajectory of viewed movements as action unfolded, although less accurately than during performance. ‘View’ neurons became less active and contained poorer representations of action when viewing only sub-components of the task. MI ‘view’ neurons thus appear to reflect the aspects of a learned movement when observed in others and form part of a broadly engaged set of cortical areas routinely responding to learned behaviors. These findings suggest that viewing a learned action elicits replay of aspects of MI activity needed to perform the observed action and could additionally reflect processing related to understanding, learning or mentally rehearsing action.
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DOI：
10.1016/s0013-4694(98)00071-6
发表时间：
1998-10-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
Cochin, S;Barthelemy, C;Martineau, J
通讯作者：
Martineau, J
影响因子：
56.9
作者：
Iacoboni, M;Woods, RP;Rizzolatti, G
通讯作者：
Rizzolatti, G
DOI：
10.1073/pnas.2037719100
发表时间：
2003-10-14
影响因子：
11.1
作者：
Amirikian, B;Georgopoulos, AP
通讯作者：
Georgopoulos, AP
DOI：
10.1073/pnas.0702453104
发表时间：
2007-05-22
影响因子：
11.1
作者：
Caetano, Gina;Jousmaki, Veikko;Hari, Riitta
通讯作者：
Hari, Riitta
影响因子：
64.8
作者：
Cisek, P;Kalaska, JF
通讯作者：
Kalaska, JF