Relationship between physical activity and stiff or painful joints in mid-aged women and older women: a 3-year prospective study.

Relationship between physical activity and stiff or painful joints in mid-aged women and older women: a 3-year prospective study.
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DOI:
10.1186/ar2154
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发表时间:
2007
影响因子:
4.9
通讯作者:
Brown WJ
Brown WJ
中科院分区:
医学2区
文献类型:
--
作者:
Heesch KC;Miller YD;Brown WJ

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这项前瞻性研究调查了3年内中年妇女和老年妇女身体活动与自我报告的关节僵硬或疼痛(SPJ)发生率之间的关系。数据收集自中年(时间1时为48-55岁; n = 4,780)和老年妇女(时间1时为72-79岁; n = 3,970)的队列,这些妇女间隔3年完成了澳大利亚妇女健康纵向研究的邮寄调查。身体活动是用Active Australia问题测量的,并根据每周代谢当量值分钟数进行分类:无(<40 MET.min/周);非常低(40至<300 MET.min/周);低(300至<600 MET.min/周);中度(600至<1,200 MET.min/周);和高(1,200 + MET.min/周)。队列特异性逻辑回归模型用于检查时间1的体力活动与SPJ“有时或经常”之间的关联,以及时间2的单独“经常”之间的关联。在时间1报告SPJ“有时或经常”的受访者被排除在分析之外。在单变量模型中,报告SPJ“有时或经常”的几率较低,(比值比(OR)= 0.77,95%置信区间(CI)= 0.63-0.94),中度(OR = 0.82,95%CI = 0.68-0.99),高(OR = 0.75,95%CI = 0.62-0.90)体力活动水平和中度体力活动的老年受访者(OR = 0.80,95% CI = 0.65-0.98)或高活动(OR = 0.83,95% CI = 0.69-0.99)的患者比久坐的患者多。调整混杂因素后,这些关联不再具有统计学意义。在单变量但未调整的模型中,中等活动的中年受访者报告SPJ“经常”的几率(OR = 0.71,95%CI = 0.52-0.97)低于久坐的受访者。低收入家庭的老年妇女(OR = 0.72,95% CI = 0.55-0.96),中度(OR = 0.54,95%CI = 0.39-0.76),高(OR = 0.61,95%CI = 0.46-0.82)体力活动类别在时间2时报告SPJ“经常”的几率低于久坐不动者,即使在调整混杂因素之后。这些结果首次显示了老年妇女体力活动和关节炎症状之间的剂量反应关系。他们建议,对目前未出现SPJ的老年妇女的建议应包括常规的身体活动对预防这些症状发作的重要性的咨询。
This prospective study examined the association between physical activity and the incidence of self-reported stiff or painful joints (SPJ) among mid-age women and older women over a 3-year period. Data were collected from cohorts of mid-age (48–55 years at Time 1; n = 4,780) and older women (72–79 years at Time 1; n = 3,970) who completed mailed surveys 3 years apart for the Australian Longitudinal Study on Women's Health. Physical activity was measured with the Active Australia questions and categorized based on metabolic equivalent value minutes per week: none (<40 MET.min/week); very low (40 to <300 MET.min/week); low (300 to <600 MET.min/week); moderate (600 to <1,200 MET.min/week); and high (1,200+ MET.min/week). Cohort-specific logistic regression models were used to examine the association between physical activity at Time 1 and SPJ 'sometimes or often' and separately 'often' at Time 2. Respondents reporting SPJ 'sometimes or often' at Time 1 were excluded from analysis. In univariate models, the odds of reporting SPJ 'sometimes or often' were lower for mid-age respondents reporting low (odds ratio (OR) = 0.77, 95% confidence interval (CI) = 0.63–0.94), moderate (OR = 0.82, 95% CI = 0.68–0.99), and high (OR = 0.75, 95% CI = 0.62–0.90) physical activity levels and for older respondents who were moderately (OR = 0.80, 95% CI = 0.65–0.98) or highly active (OR = 0.83, 95% CI = 0.69–0.99) than for those who were sedentary. After adjustment for confounders, these associations were no longer statistically significant. The odds of reporting SPJ 'often' were lower for mid-age respondents who were moderately active (OR = 0.71, 95% CI = 0.52–0.97) than for sedentary respondents in univariate but not adjusted models. Older women in the low (OR = 0.72, 95% CI = 0.55–0.96), moderate (OR = 0.54, 95% CI = 0.39–0.76), and high (OR = 0.61, 95% CI = 0.46–0.82) physical activity categories had lower odds of reporting SPJ 'often' at Time 2 than their sedentary counterparts, even after adjustment for confounders. These results are the first to show a dose–response relationship between physical activity and arthritis symptoms in older women. They suggest that advice for older women not currently experiencing SPJ should routinely include counseling on the importance of physical activity for preventing the onset of these symptoms.
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