Advances in Chronic Obstructive Pulmonary Disease.
Advances in Chronic Obstructive Pulmonary Disease.
复制标题
慢性阻塞性肺疾病研究进展。
DOI:
10.1146/annurev-med-080919-112707
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发表时间:
2021-01-27
影响因子:
10.5
通讯作者:
Han MK
中科院分区:
文献类型:
--
作者:
Ferrera MC;Labaki WW;Han MK
Chronic obstructive pulmonary disease (COPD) is a common respiratory disorder with significant morbidity and mortality. Despite its prevalence, COPD is underdiagnosed, and many patients do not receive a diagnosis until the disease is clinically advanced. Recent basic science and clinical research have focused on the early physiologic and pathobiologic changes in COPD with the hopes of improving diagnosis, providing targets for disease-modifying therapy, and identifying patients most likely to benefit from early intervention. Available treatments for COPD have grown substantially in the past 20 years with the introduction of new oral and inhaled medications as well as novel surgical and bronchoscopic procedures. This article summarizes some of the recent advances in our understanding of disease pathogenesis and treatment paradigms.
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