Clinical Features and Visual Acuity Outcomes in Culture-Positive Endogenous Fungal Endophthalmitis in Southern China.

Clinical Features and Visual Acuity Outcomes in Culture-Positive Endogenous Fungal Endophthalmitis in Southern China.
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中国南方培养阳性内源性真菌性眼内炎的临床特征和视力结果

DOI:
10.1155/2017/3483497
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发表时间:
2017
影响因子:
1.9
通讯作者:
Lin X
Lin X
中科院分区:
医学4区
文献类型:
--
作者:
Duan F;Yang Y;Yuan Z;Zheng Y;Cheng Z;Lin X

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目的 报告来自中国南方的一系列病例中经培养证实的内源性真菌性眼内炎的病原体、管理策略和视觉结果。方法 我们回顾了 2006 年 1 月 1 日至 2016 年 3 月 31 日期间就诊于中国广州市中山眼科中心的培养阳性内源性真菌性眼内炎患者的微生物学和医疗记录。结果 29 名患者的 32 只眼睛符合纳入标准。霉菌是 15 名患者(51.7%)的常见致病菌,而酵母菌则出现在 14 名患者(48.3%)中。手指计数水平或更好的初始视力 (VA) 与良好的视力结果显着相关 (P = 0.002)。与酵母相比,霉菌作为病原体与更差的视觉结果显着相关(P = 0.020)。结论 霉菌是培养证实的真菌性眼内炎的常见原因。内源性真菌性眼内炎通常与视力不佳结果相关,尤其是由霉菌引起且患者初​​始视力过低而无法进行手指计数时。
Purpose To report the causative organisms, management strategies, and visual outcomes of culture-proven endogenous fungal endophthalmitis in a case series from southern China. Methods We reviewed the microbiological and medical records of patients with culture-positive endogenous fungal endophthalmitis visiting the Zhongshan Ophthalmic Center, Guangzhou, China, between January 1, 2006, and March 31, 2016. Results The inclusion criteria were met in 32 eyes of 29 patients. Molds were a common causative organism in 15 patients (51.7%), while yeasts appeared in 14 patients (48.3%). Initial visual acuity (VA) at the level of finger counting or better was significantly related to a good visual outcome (P = 0.002). Molds as a causative agent were significantly associated with worse visual outcome than yeasts (P = 0.020). Conclusion Molds were a common cause of culture-proven fungal endophthalmitis. Endogenous fungal endophthalmitis is generally associated with poor VA outcomes, especially if caused by molds and if the patient's initial VA is too low to permit finger counting.
内源性真菌性内膜:霉菌和酵母菌感染中的危险因素,临床特征和治疗结果。
DOI: 10.1186/1869-5760-3-60
发表时间: 2013-09-20
影响因子: 2.9
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影响因子: 5
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