KEGG for linking genomes to life and the environment.
KEGG for linking genomes to life and the environment.
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DOI：
10.1093/nar/gkm882
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发表时间：
2008-01
影响因子：
14.9
通讯作者：
Yamanishi Y
中科院分区：
文献类型：
--
作者：
Kanehisa M;Araki M;Goto S;Hattori M;Hirakawa M;Itoh M;Katayama T;Kawashima S;Okuda S;Tokimatsu T;Yamanishi Y
KEGG（http：//www.genome.jp/kegg/）是一个生物系统数据库，它整合了基因组、化学和系统功能信息。KEGG提供了一个参考知识库，用于通过PATHWAY映射过程将基因组与生命联系起来，PATHWAY映射过程是将例如基因的基因组或转录组内容映射到KEGG参考途径，以推断细胞或生物体的系统行为。此外，KEGG提供了一个参考知识库，用于将基因组与环境联系起来，例如通过BRITE映射过程分析药物-靶标关系。KEGG BRITE是一个本体数据库，代表各种生物对象的功能层次，包括分子，细胞，生物体，疾病和药物，以及它们之间的关系。KEGG PATHWAY现在补充了一个新的全球代谢途径图，这基本上是一个约120个现有途径图的组合图。此外，更小的通路模块被定义并存储在KEGG MODITOR中，KEGG MODITOR还包含其他功能单元和复合物。KEGG资源正在扩大，以满足实际应用的需要。KEGG DRUG包含美国和日本批准的所有药物，KEGG DISEASE是一个新的数据库，将疾病基因、途径、药物和诊断标志物联系起来。
KEGG (http://www.genome.jp/kegg/) is a database of biological systems that integrates genomic, chemical and systemic functional information. KEGG provides a reference knowledge base for linking genomes to life through the process of PATHWAY mapping, which is to map, for example, a genomic or transcriptomic content of genes to KEGG reference pathways to infer systemic behaviors of the cell or the organism. In addition, KEGG provides a reference knowledge base for linking genomes to the environment, such as for the analysis of drug-target relationships, through the process of BRITE mapping. KEGG BRITE is an ontology database representing functional hierarchies of various biological objects, including molecules, cells, organisms, diseases and drugs, as well as relationships among them. KEGG PATHWAY is now supplemented with a new global map of metabolic pathways, which is essentially a combined map of about 120 existing pathway maps. In addition, smaller pathway modules are defined and stored in KEGG MODULE that also contains other functional units and complexes. The KEGG resource is being expanded to suit the needs for practical applications. KEGG DRUG contains all approved drugs in the US and Japan, and KEGG DISEASE is a new database linking disease genes, pathways, drugs and diagnostic markers.
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影响因子：
5.8
作者：
Limviphuvadh, Vachiranee;Tanaka, Seigo;Kanehisa, Minoru
通讯作者：
Kanehisa, Minoru
影响因子：
5.8
作者：
Kawano, S;Hashimoto, K;Kanehisa, M
通讯作者：
Kanehisa, M
影响因子：
56.9
作者：
FLEISCHMANN, RD;ADAMS, MD;VENTER, JC
通讯作者：
VENTER, JC
影响因子：
5.6
作者：
Oh, Mina;Yamada, Takuji;Kanehisa, Minoru
通讯作者：
Kanehisa, Minoru
KAAS：自动基因组注释和路径重建服务器。
影响因子：
14.9
作者：
Moriya Y;Itoh M;Okuda S;Yoshizawa AC;Kanehisa M
通讯作者：
Kanehisa M