Reovirus type 1 is secreted into the bile

Reovirus type 1 is secreted into the bile
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1 型呼肠孤病毒分泌到胆汁中

DOI:
10.1128/jvi.60.2.726-728.1986
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发表时间:
1986
影响因子:
5.4
通讯作者:
T. Costello
T. Costello
中科院分区:
医学2区
文献类型:
--
作者:
D. Rubin;M. Eaton;T. Costello

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呼肠孤病毒1型,已知是引起小鼠全身和肠道疾病的原因,在病毒血症后被分泌到成年a /J小鼠的胆汁中。在胆汁中发现的病毒浓度高于血液中的病毒浓度可能表明呼肠孤病毒1型被积极地转运到胆汁中。病毒的转运与病毒特异性免疫球蛋白A抗体水平无关。在运输过程中发生的病毒修饰对病毒的传染性没有明显的影响。病毒进入胆汁可能是引起全身性疾病的肠道病毒重新进入肠道传播的重要机制。
Reovirus type 1, known to be a cause of systemic and intestinal disease in mice, is secreted into the bile of adult A/J mice after viremia. Virus found in the bile in concentrations higher than those in blood may indicate that reovirus type 1 is actively transported into the bile. The transport of virus was independent of levels of virus-specific immunoglobulin A antibody. Modifications of the virus that occurred during transport did not discernibly affect the infectivity of the virus. Entry of virus into the bile may be an important mechanism by which an enteric virus that produces systemic disease reenters the intestine for transmission.
DOI: 10.1126/science.6259737
发表时间: 1981-01-01
期刊: SCIENCE
影响因子: 56.9
作者:
WOLF, JL;RUBIN, DH;FIELDS, BN
通讯作者: FIELDS, BN
通过 IgA 将肠道吸收的抗原消除到胆汁中。
DOI: --
发表时间: 1984
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Brown,TA;Russell,MW;Mestecky,J
通讯作者: Mestecky,J
呼肠孤病毒与小鼠肠道肠道 M 细胞和吸收细胞相互作用的决定因素。
DOI: --
发表时间: 1983
期刊: Gastroenterology
影响因子: 29.4
作者:
Wolf,JL;Kauffman,RS;Finberg,R;Dambrauskas,R;Fields,BN;Trier,JS
通讯作者: Trier,JS