A genetic history of the pre-contact Caribbean.
A genetic history of the pre-contact Caribbean.
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接触前加勒比地区的遗传史。
DOI：
10.1038/s41586-020-03053-2
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发表时间：
2021-03
期刊：
影响因子：
64.8
通讯作者：
Reich D
中科院分区：
文献类型：
--
作者：
Fernandes DM;Sirak KA;Ringbauer H;Sedig J;Rohland N;Cheronet O;Mah M;Mallick S;Olalde I;Culleton BJ;Adamski N;Bernardos R;Bravo G;Broomandkhoshbacht N;Callan K;Candilio F;Demetz L;Carlson KSD;Eccles L;Freilich S;George RJ;Lawson AM;Mandl K;Marzaioli F;McCool WC;Oppenheimer J;Özdogan KT;Schattke C;Schmidt R;Stewardson K;Terrasi F;Zalzala F;Antúnez CA;Canosa EV;Colten R;Cucina A;Genchi F;Kraan C;La Pastina F;Lucci M;Maggiolo MV;Marcheco-Teruel B;Maria CT;Martínez C;París I;Pateman M;Simms TM;Sivoli CG;Vilar M;Kennett DJ;Keegan WF;Coppa A;Lipson M;Pinhasi R;Reich D
约6000年前，人类在加勒比海定居，陶器的使用和集约化农业标志着约2500年前从古代到陶器时代的转变。我们报告了来自巴哈马、伊斯帕尼奥拉、波多黎各、库拉索和委内瑞拉的174个人的全基因组数据，并与已发表的数据进行了联合分析。古老时代加勒比人起源于最接近中南美洲和北美洲的高度分化的人口；与之前的工作相反，我们发现与北美有血缘关系的人口没有祖先的支持。古老的血统98%被来自南美洲东北部的说阿拉瓦克语的基因同质的使用陶瓷的人群所取代，他们至少在1700年前穿过小安的列斯群岛进入大安的列斯群岛，引入了至今仍存在的祖先。古代加勒比人避免近亲结合，尽管有限的配偶池反映了小的有效人口规模，我们估计在被分析的个人生活之前的几十代人中，波多黎各和伊斯帕尼奥拉岛合并的岛屿上的最小Ne=500-1500和最大Ne=1530-8150。人口普查规模不太可能超过有效人口规模的十倍，因此之前估计的数十万人太多了。我们确认了一个小的、相互关联的陶瓷时代种群，我们检测到19对跨岛表亲，在伊斯帕尼奥拉相距约75公里的近亲，以及跨岛屿的低遗传分化。陶器风格转变中的遗传连续性表明，陶瓷时代的文化变化并不是由来自大陆的遗传差异群体的移民推动的，而是反映了一个相互联系的加勒比海世界的互动。
Humans settled the Caribbean ~6,000 years ago, with ceramic use and intensified agriculture marking a shift from the Archaic to the Ceramic Age ~2,500 years ago. We report genome-wide data from 174 individuals from The Bahamas, Hispaniola, Puerto Rico, Curaçao, and Venezuela co-analyzed with published data. Archaic Age Caribbean people derive from a deeply divergent population closest to Central and northern South Americans; contrary to previous work, we find no support for ancestry contributed by a population related to North Americans. Archaic lineages were >98% replaced by a genetically homogeneous ceramic-using population related to Arawak-speakers from northeast South America who moved through the Lesser Antilles and into the Greater Antilles at least 1,700 years ago, introducing ancestry that is still present. Ancient Caribbean people avoided close kin unions despite limited mate pools reflecting small effective population sizes which we estimate to be a minimum of Ne=500–1500 and a maximum of Ne=1530–8150 on the combined islands of Puerto Rico and Hispaniola in the dozens of generations before the analyzed individuals lived. Census sizes are unlikely to be more than ten-fold larger than effective population sizes, so previous estimates of hundreds of thousands of people are too large. Confirming a small, interconnected Ceramic Age population, we detect 19 pairs of cross-island cousins, close relatives ~75 kilometers apart in Hispaniola, and low genetic differentiation across islands. Genetic continuity across transitions in pottery styles reveals that cultural changes during the Ceramic Age were not driven by migration of genetically-differentiated groups from the mainland but instead reflected interactions within an interconnected Caribbean world.
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影响因子：
16.6
作者：
Kennett DJ;Plog S;George RJ;Culleton BJ;Watson AS;Skoglund P;Rohland N;Mallick S;Stewardson K;Kistler L;LeBlanc SA;Whiteley PM;Reich D;Perry GH
通讯作者：
Perry GH
影响因子：
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通讯作者：
Browning, Brian L.
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通讯作者：
Reich D
影响因子：
9.2
作者：
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通讯作者：
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