Aortic valve imaging using (18)F-sodium fluoride: impact of triple motion correction.
Aortic valve imaging using (18)F-sodium fluoride: impact of triple motion correction.
复制标题
使用(18)F-氟化钠的主动脉瓣成像：三重运动校正的影响。
DOI：
10.1186/s40658-022-00433-7
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发表时间：
2022-01-29
期刊：
影响因子：
4
通讯作者：
Slomka PJ
中科院分区：
文献类型：
--
作者：
Lassen ML;Tzolos E;Massera D;Cadet S;Bing R;Kwiecinski J;Dey D;Berman DS;Dweck MR;Newby DE;Slomka PJ
目前使用18F-NaF PET/CT对主动脉瓣微钙化的18F-NaF评估是基于舒张末期或心脏运动校正（ECG-MC）图像的评价，这些图像受患者和呼吸运动的影响。我们的目的是测试采用三重运动校正技术（3 × MC）（包括心肺运动和总体患者运动）对定量和定性测量的影响。14例主动脉瓣狭窄患者在（29 ± 24）d内进行了2次30 min PET主动脉瓣扫描。我们考虑了三种不同的图像重建协议;舒张末期重建协议（标准）利用25%的采集数据，ECG门控（四个ECG门）重建（ECG-MC）和三重运动校正（3 × MC）数据集，用于校正心肺和患者运动。将所有数据集与使用Agatston方法从CT扫描中获得的主动脉瓣钙化评分（AVCS）进行比较。我们报告了在主动脉瓣中测量的SUVmax值和校正血池活性后的最大目标背景比（TBRmax）值。与标准和ECG-MC重建相比，在3 × MC后观察到SUVmax和TBRmax增加（SUVmax：标准= 2.8 ± 0.7，ECG-MC = 2.6 ± 0.6，3 × MC = 3.3 ± 0.9; TBRmax：标准品= 2.7 ± 0.7，ECG-MC = 2.5 ± 0.6和3 × MC = 3.3 ± 1.2，所有p值≤ 0.05）。与标准方法相比，3 × MC与AVCS的相关性（R2值）有所改善（SUVmax：标准= 0.10，ECG-MC = 0.10和3 × MC = 0.20; TBRmax：标准= 0.20，ECG-MC = 0.28和3 × MC = 0.46）。3 × MC改善了AVCS与SUVmax和TBRmax之间的相关性，在使用18F-NaF进行主动脉瓣PET研究时应予以考虑。在线版本包含补充材料，可通过10.1186/s40658-022-00433-7获得。
Current 18F-NaF assessments of aortic valve microcalcification using 18F-NaF PET/CT are based on evaluations of end-diastolic or cardiac motion-corrected (ECG-MC) images, which are affected by both patient and respiratory motion. We aimed to test the impact of employing a triple motion correction technique (3 × MC), including cardiorespiratory and gross patient motion, on quantitative and qualitative measurements. Fourteen patients with aortic stenosis underwent two repeat 30-min PET aortic valve scans within (29 ± 24) days. We considered three different image reconstruction protocols; an end-diastolic reconstruction protocol (standard) utilizing 25% of the acquired data, an ECG-gated (four ECG gates) reconstruction (ECG-MC), and a triple motion-corrected (3 × MC) dataset which corrects for both cardiorespiratory and patient motion. All datasets were compared to aortic valve calcification scores (AVCS), using the Agatston method, obtained from CT scans using correlation plots. We report SUVmax values measured in the aortic valve and maximum target-to-background ratios (TBRmax) values after correcting for blood pool activity. Compared to standard and ECG-MC reconstructions, increases in both SUVmax and TBRmax were observed following 3 × MC (SUVmax: Standard = 2.8 ± 0.7, ECG-MC = 2.6 ± 0.6, and 3 × MC = 3.3 ± 0.9; TBRmax: Standard = 2.7 ± 0.7, ECG-MC = 2.5 ± 0.6, and 3 × MC = 3.3 ± 1.2, all p values ≤ 0.05). 3 × MC had improved correlations (R2 value) to the AVCS when compared to the standard methods (SUVmax: Standard = 0.10, ECG-MC = 0.10, and 3 × MC = 0.20; TBRmax: Standard = 0.20, ECG-MC = 0.28, and 3 × MC = 0.46). 3 × MC improves the correlation between the AVCS and SUVmax and TBRmax and should be considered in PET studies of aortic valves using 18F-NaF. The online version contains supplementary material available at 10.1186/s40658-022-00433-7.
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影响因子：
5.9
作者：
Peeters, Frederique E. C. M.;van Mourik, Manouk J. W.;Kietselaer, Bas L. J. H.
通讯作者：
Kietselaer, Bas L. J. H.
DOI：
10.1007/s00259-010-1533-y
发表时间：
2010-12-01
影响因子：
9.1
作者：
Buether, Florian;Ernst, Iris;Schaefers, Klaus P.
通讯作者：
Schaefers, Klaus P.
影响因子：
2.4
作者：
Nakamoto, Yumiko;Kitagawa, Toshiro;Kihara, Yasuki
通讯作者：
Kihara, Yasuki
DOI：
10.1161/circimaging.116.005131
发表时间：
2016-10
期刊：
Circulation. Cardiovascular imaging
影响因子：
--
作者：
Pawade TA;Cartlidge TR;Jenkins WS;Adamson PD;Robson P;Lucatelli C;Van Beek EJ;Prendergast B;Denison AR;Forsyth L;Rudd JH;Fayad ZA;Fletcher A;Tuck S;Newby DE;Dweck MR
通讯作者：
Dweck MR
影响因子：
2.4
作者：
Lassen, Martin Lyngby;Beyer, Thomas;Cal-Gonzalez, Jacobo
通讯作者：
Cal-Gonzalez, Jacobo