Spoken language outcome measures for treatment studies in Down syndrome: feasibility, practice effects, test-retest reliability, and construct validity of variables generated from expressive language sampling.

Spoken language outcome measures for treatment studies in Down syndrome: feasibility, practice effects, test-retest reliability, and construct validity of variables generated from expressive language sampling.
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DOI:
10.1186/s11689-021-09361-6
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发表时间:
2021-04-08
影响因子:
4.9
通讯作者:
Abbeduto L
Abbeduto L
中科院分区:
医学2区
文献类型:
--
作者:
Thurman AJ;Edgin JO;Sherman SL;Sterling A;McDuffie A;Berry-Kravis E;Hamilton D;Abbeduto L

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本研究的目的是评估表达性语言采样(ELS)作为一种程序,产生口语的治疗研究唐氏综合征(DS)的结果措施。我们解决了(a)可行性,(B)实践效果在两个短期管理,(c)重测信度在两个短期管理,(d)收敛和判别结构效度,(e)考虑在会话和叙述的情况下进行比较。 参与者是107名年龄在6至23岁之间的DS患者,他们患有智力残疾(IQ < 70)。ELS程序的效用,旨在收集样本的口头语言在对话和叙述分别进行了评估。从分割成C单元的转录本(即,独立条款及其修饰语)。一个4周的时间间隔被用来评估实践效果和重测信度。收集标准化的直接评估和举报人报告措施,以评估ELS变量的结构效度。观察到的不依从率较低;年龄在12岁以下,言语水平不超过短语水平,发育水平不超过4岁的青少年在完成ELS程序时遇到困难的风险特别大。最小的实践效果和强大的重测信度在4周的重测间隔进行了观察。词汇,句法和语音清晰度变量表现出很强的收敛性和判别效度。虽然显着的相关性之间的变量来自两个会话和叙述的情况下,也注意到一些差异。ELS程序被认为是可行的,并产生了足够的心理测量特性的变量,大多数人与DS之间的6和23岁。也就是说,需要研究适合于具有更有限的口语技能的DS患者的结果措施。ELS变量中的上下文差异表明,表达性语言的综合评价可能是最好的利用这两种情况下获得。
The purpose of this study was to evaluate expressive language sampling (ELS) as a procedure for generating spoken language outcome measures for treatment research in Down syndrome (DS). We addressed (a) feasibility, (b) practice effects across two short-term administrations, (c) test-retest reliability across two short-term administrations, (d) convergent and discriminant construct validity, and (e) considered comparisons across the conversation and narration contexts. Participants were 107 individuals with DS between 6 and 23 years of age who presented with intellectual disability (IQ < 70). The utility of ELS procedures designed to collect samples of spoken language in conversation and narration were evaluated separately. Variables of talkativeness, vocabulary, syntax, utterance planning, and articulation quality, derived from transcripts segmented into C-units (i.e., an independent clause and its modifiers), were considered. A 4-week interval was used to assess practice effects and test-retest reliability. Standardized direct assessments and informant report measures were collected to evaluate construct validity of the ELS variables. Low rates of noncompliance were observed; youth who were under 12 years of age, had phrase-level speech or less, and had a 4-year-old developmental level or less were at particular risk for experiencing difficulty completing the ELS procedures. Minimal practice effects and strong test-retest reliability across the 4-week test-retest interval was observed. The vocabulary, syntax, and speech intelligibility variables demonstrated strong convergent and discriminant validity. Although significant correlations were found between the variables derived from both the conversation and narration contexts, some differences were noted. The ELS procedures considered were feasible and yielded variables with adequate psychometric properties for most individuals with DS between 6 and 23 years old. That said, studies of outcome measures appropriate for individuals with DS with more limited spoken language skills are needed. Context differences were observed in ELS variables suggest that comprehensive evaluation of expressive language is likely best obtained when utilizing both contexts.
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