Interplay between miRNAs and lncRNAs: Mode of action and biological roles in plant development and stress adaptation.

Interplay between miRNAs and lncRNAs: Mode of action and biological roles in plant development and stress adaptation.
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miRNA 和 lncRNA 之间的相互作用:植物发育和逆境适应中的作用模式和生物学作用

DOI:
10.1016/j.csbj.2021.04.062
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发表时间:
2021
影响因子:
6
通讯作者:
Li S
Li S
中科院分区:
生物学2区
文献类型:
--
作者:
Meng X;Li A;Yu B;Li S

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植物利用复杂的机制来控制发育过程,并在转录和转录后水平上应对环境变化。微小RNAs(MiRNAs)和长非编码RNAs(LncRNAs)是两类内源非编码RNAs,是植物基因表达的关键调控因子。最近的研究发现,miRNAs和lncRNAs之间的相互作用是植物基因表达的一个新的调节层。一方面,miRNAs以lncRNAs为靶点,产生阶段性小干扰RNAs(PhasiRNAs)。另一方面,lncRNAs作为miRNAs的来源或在转录和转录后水平上调节miRNAs的积累或活性。这些lncRNA-miRNA相互作用对于植物的发育、生理以及对生物和非生物胁迫的响应都是至关重要的。本文综述了植物中miRNAs和lncRNAs相互作用的生物学作用、相互作用机制和计算预测方法的最新研究进展。
Plants employ sophisticated mechanisms to control developmental processes and to cope with environmental changes at transcriptional and post-transcriptional levels. MicroRNAs (miRNAs) and long noncoding RNAs (lncRNAs), two classes of endogenous noncoding RNAs, are key regulators of gene expression in plants. Recent studies have identified the interplay between miRNAs and lncRNAs as a novel regulatory layer of gene expression in plants. On one hand, miRNAs target lncRNAs for the production of phased small interfering RNAs (phasiRNAs). On the other hand, lncRNAs serve as origin of miRNAs or regulate the accumulation or activity of miRNAs at transcription and post-transcriptional levels. Theses lncRNA-miRNA interplays are crucial for plant development, physiology and responses to biotic and abiotic stresses. In this review, we summarize recent advances in the biological roles, interaction mechanisms and computational predication methods of the interplay between miRNAs and lncRNAs in plants.
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