MicroRNA misregulation: an overlooked factor generating somaclonal variation?
MicroRNA misregulation: an overlooked factor generating somaclonal variation?
复制标题
MicroRNA 失调:一个被忽视的产生体细胞克隆变异的因素?
DOI:
10.1016/j.tplants.2011.03.002
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发表时间:
2011
影响因子:
20.5
通讯作者:
Rodriguez-Enriquez J
中科院分区:
文献类型:
--
作者:
Rodriguez-Enriquez J
Somaclonal variation is an important phenomenon that can be observed at high levels in plant tissue culture. Although known to science since plant cell culture techniques were first developed, its origins remain mysterious. Here, we propose that misregulation of microRNAs and small RNA pathways can make a significant contribution to the phenomenon. For many reasons, microRNAs and related small RNAs appear ideal candidates. Their mode of action gives them disproportionate influence over the transcriptome, proteome and epigenome. They regulate important developmental and physiological events such as meristem formation, phase changes and hormone responses. However, the genomic locations of microRNA genes and their unique biogenesis might make them unusually susceptible to aberrant regulationin vitro.
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DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
M. Zalewska;N. Miler;A. Wenda
通讯作者:
A. Wenda
影响因子:
3.3
作者:
I. Mitsuhara;Naomi Shirasawa-Seo;T. Iwai;Shigeo Nakamura;R. Honkura;Y. Ohashi
通讯作者:
I. Mitsuhara;Naomi Shirasawa-Seo;T. Iwai;Shigeo Nakamura;R. Honkura;Y. Ohashi
DOI:
--
发表时间:
1969
期刊:
影响因子:
--
作者:
D. Spencer;W. Kimmins
通讯作者:
W. Kimmins
DOI:
--
发表时间:
2007
期刊:
In Vitro Cellular & Developmental Biology - Plant
影响因子:
--
作者:
Li;C. Hsiao;Shu;Bau;T. Murashige
通讯作者:
T. Murashige
影响因子:
1.9
作者:
R. Skirvin
通讯作者:
R. Skirvin