Roadmap for future research on plant pathogen effectors.
Roadmap for future research on plant pathogen effectors.
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未来研究植物病原体效应子的路线图。
DOI：
10.1111/j.1364-3703.2009.00588.x
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发表时间：
2009-11
影响因子：
4.9
通讯作者：
Alfano, James R.
中科院分区：
文献类型：
--
作者：
Alfano, James R.
细菌和真核植物病原体将效应蛋白递送到植物细胞中以促进致病。已知含有III型蛋白质分泌系统的细菌病原体将许多这些效应物注射到植物细胞中。最近，卵菌病原体已被证明拥有一个大家族的效应器含有RXLR基序，许多效应器也被发现在真菌病原体。虽然效应活性在很大程度上是未知的，至少有一个子集抑制植物免疫。得益于下一代测序技术，大量新的植物病原体基因组将很快可用，这将允许识别更多的效应子。本文总结了用于鉴定植物病原体效应子的关键方法，其中许多方法将继续用于未来的效应子发现。因此，它可以被视为一个'路线图'效应器和效应器的目标识别。由于效应子可以用作阐明先天免疫成分的工具，因此我们对效应子及其靶点的了解的进步应该会带来农业的改进。
Bacterial and eukaryotic plant pathogens deliver effector proteins into plant cells to promote pathogenesis. Bacterial pathogens containing type III protein secretion systems are known to inject many of these effectors into plant cells. More recently, oomycete pathogens have been shown to possess a large family of effectors containing the RXLR motif, and many effectors are also being discovered in fungal pathogens. Although effector activities are largely unknown, at least a subset suppress plant immunity. A plethora of new plant pathogen genomes that will soon be available thanks to next-generation sequencing technologies will allow the identification of many more effectors. This article summarizes the key approaches used to identify plant pathogen effectors, many of which will continue to be useful for future effector discovery. Thus, it can be viewed as a ‘roadmap’ for effector and effector target identification. Because effectors can be used as tools to elucidate components of innate immunity, advances in our understanding of effectors and their targets should lead to improvements in agriculture.
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影响因子：
6.7
作者：
Angot, Aurelie;Vergunst, Annette;Genin, Stephane;Peeters, Nemo
通讯作者：
Peeters, Nemo
DOI：
10.1073/pnas.0509393103
发表时间：
2006-09-26
影响因子：
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作者：
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作者：
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通讯作者：
Alfano, James R.