Synaptic unreliability facilitates information transmission in balanced cortical populations.
Synaptic unreliability facilitates information transmission in balanced cortical populations.
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突触不可靠性有利于平衡皮质群中的信息传输。
DOI:
10.1103/physreve.91.062707
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发表时间:
2015
期刊:
影响因子:
--
通讯作者:
M. Bethge
中科院分区:
文献类型:
--
作者:
Leon A. Gatys;Alexander S. Ecker;T. Tchumatchenko;M. Bethge
Synaptic unreliability is one of the major sources of biophysical noise in the brain. In the context of neural information processing, it is a central question how neural systems can afford this unreliability. Here we examine how synaptic noise affects signal transmission in cortical circuits, where excitation and inhibition are thought to be tightly balanced. Surprisingly, we find that in this balanced state synaptic response variability actually facilitates information transmission, rather than impairing it. In particular, the transmission of fast-varying signals benefits from synaptic noise, as it instantaneously increases the amount of information shared between presynaptic signal and postsynaptic current. Furthermore we show that the beneficial effect of noise is based on a very general mechanism which contrary to stochastic resonance does not reach an optimum at a finite noise level.
DOI:
10.1073/pnas.91.22.10380
发表时间:
1994-10-25
影响因子:
11.1
作者:
ALLEN, C;STEVENS, CF
通讯作者:
STEVENS, CF
影响因子:
8.6
作者:
Nikitin, Alexander P.;Stocks, Nigel G.;McDonnell, Mark D.
通讯作者:
McDonnell, Mark D.
DOI:
10.1073/pnas.87.14.5359
发表时间:
1990-07-01
影响因子:
11.1
作者:
BEKKERS, JM;RICHERSON, GB;STEVENS, CF
通讯作者:
STEVENS, CF