Converging Evidence From Electrocorticography and BOLD fMRI for a Sharp Functional Boundary in Superior Temporal Gyrus Related to Multisensory Speech Processing.
Converging Evidence From Electrocorticography and BOLD fMRI for a Sharp Functional Boundary in Superior Temporal Gyrus Related to Multisensory Speech Processing.
复制标题
DOI：
10.3389/fnhum.2018.00141
复制
发表时间：
2018
影响因子：
2.9
通讯作者：
Beauchamp MS
中科院分区：
文献类型：
--
作者：
Ozker M;Yoshor D;Beauchamp MS
虽然人类可以单独使用听觉模态来理解语音，但在嘈杂的环境中，来自说话者口中的视觉语音信息可以拯救否则难以理解的听觉语音。为了研究多感觉言语知觉的神经基础，我们比较了两个数据集中人类上级颞回（STG）的神经活动。一个数据集由植入癫痫患者的表面电极的直接神经记录（皮层电图，ECoG）组成（该数据集先前已发表）。第二个数据集包括使用血氧水平依赖性功能磁共振成像（BOLD fMRI）的神经活动的间接测量。ECoG和fMRI参与者都观看了相同的清晰和嘈杂的视听语音刺激，并执行了相同的语音识别任务。这两种技术都显示了STG中的尖锐功能边界，在空间上与由Heschl回后缘定义的解剖边界一致。边界前侧的皮层对清晰的视听语音的反应比对嘈杂的视听语音的反应更强烈，而边界后侧的皮层则没有。对于ECoG和fMRI测量，功能不同的区域之间的过渡发生在10 mm的前后距离沿着STG。我们将此边界与语音感知的多感觉神经编码联系起来，并提出它代表了人类语音感知网络中的一个重要功能分区。
Although humans can understand speech using the auditory modality alone, in noisy environments visual speech information from the talker’s mouth can rescue otherwise unintelligible auditory speech. To investigate the neural substrates of multisensory speech perception, we compared neural activity from the human superior temporal gyrus (STG) in two datasets. One dataset consisted of direct neural recordings (electrocorticography, ECoG) from surface electrodes implanted in epilepsy patients (this dataset has been previously published). The second dataset consisted of indirect measures of neural activity using blood oxygen level dependent functional magnetic resonance imaging (BOLD fMRI). Both ECoG and fMRI participants viewed the same clear and noisy audiovisual speech stimuli and performed the same speech recognition task. Both techniques demonstrated a sharp functional boundary in the STG, spatially coincident with an anatomical boundary defined by the posterior edge of Heschl’s gyrus. Cortex on the anterior side of the boundary responded more strongly to clear audiovisual speech than to noisy audiovisual speech while cortex on the posterior side of the boundary did not. For both ECoG and fMRI measurements, the transition between the functionally distinct regions happened within 10 mm of anterior-to-posterior distance along the STG. We relate this boundary to the multisensory neural code underlying speech perception and propose that it represents an important functional division within the human speech perception network.
登录
查看更多内容
影响因子：
14.5
作者：
Janszky, J;Jokeit, H;Ebner, A
通讯作者：
Ebner, A
影响因子：
16.2
作者：
Beck JM;Ma WJ;Kiani R;Hanks T;Churchland AK;Roitman J;Shadlen MN;Latham PE;Pouget A
通讯作者：
Pouget A
影响因子：
4.8
作者：
Bernstein, Lynne E.;Jiang, Jintao;Pantazis, Dimitrios;Lu, Zhong-Lin;Joshi, Anand
通讯作者：
Joshi, Anand
影响因子：
9.2
作者：
Calvert, GA;Campbell, R;Brammer, MJ
通讯作者：
Brammer, MJ
影响因子：
2.5
作者：
Foxe, JJ;Wylie, GR;Murray, MM
通讯作者：
Murray, MM