Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care.
Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care.
复制标题
糖尿病教育和自我管理计划（DESMOND）的有效性对于新诊断的2型糖尿病患者：梅利氏菌的糖尿病：三年的初级保健随机对照试验的随访。
DOI：
10.1136/bmj.e2333
复制
发表时间：
2012-04-26
期刊：
影响因子：
--
通讯作者：
Davies MJ
中科院分区：
文献类型：
--
作者：
Khunti K;Gray LJ;Skinner T;Carey ME;Realf K;Dallosso H;Fisher H;Campbell M;Heller S;Davies MJ
目的评估对新诊断的2型糖尿病患者实施单一教育和自我管理结构化计划的益处是否能持续3年。设计：一项多中心随机分组对照试验的三年随访，在初级保健中进行，在实践水平上进行随机化。在英国的13个初级保健场所设置207个一般做法。参与者824名参与者中的731名参与者有资格接受随访。收集了604名（82.6%）参与者的生物医学数据和513名（70.1%）参与者的问卷数据。干预与常规护理相比，由两名训练有素的医疗保健专业教育者在社区提供六小时的结构化小组教育计划。主要结局指标主要结局指标为糖化血红蛋白（HbA 1c）水平。次要结果是血压，体重，血脂水平，吸烟状况，体力活动，生活质量，对疾病的信念，抑郁症，糖尿病的情绪影响和三年的药物使用。结果两组患者3年时HbA 1c水平均下降。校正基线和聚类后，差异不显著（差异为-0.02，95%置信区间为-0.22至0.17）。两组在其他生物医学和生活方式结果以及药物使用方面没有差异。干预组在12个月时看到的五种健康信念中有四种的显着益处在三年时持续存在（P<0.01）。抑郁评分和生活质量在三年内没有差异。结论：对新诊断的2型糖尿病患者进行的单一项目在三年内的生物医学或生活方式结局没有差异，尽管一些疾病信念有持续改善。 试验注册当前对照试验ISRCTN 17844016。
Objective To measure whether the benefits of a single education and self management structured programme for people with newly diagnosed type 2 diabetes mellitus are sustained at three years. Design Three year follow-up of a multicentre cluster randomised controlled trial in primary care, with randomisation at practice level. Setting 207 general practices in 13 primary care sites in the United Kingdom. Participants 731 of the 824 participants included in the original trial were eligible for follow-up. Biomedical data were collected on 604 (82.6%) and questionnaire data on 513 (70.1%) participants. Intervention A structured group education programme for six hours delivered in the community by two trained healthcare professional educators compared with usual care. Main outcome measures The primary outcome was glycated haemoglobin (HbA1c) levels. The secondary outcomes were blood pressure, weight, blood lipid levels, smoking status, physical activity, quality of life, beliefs about illness, depression, emotional impact of diabetes, and drug use at three years. Results HbA1c levels at three years had decreased in both groups. After adjusting for baseline and cluster the difference was not significant (difference −0.02, 95% confidence interval −0.22 to 0.17). The groups did not differ for the other biomedical and lifestyle outcomes and drug use. The significant benefits in the intervention group across four out of five health beliefs seen at 12 months were sustained at three years (P<0.01). Depression scores and quality of life did not differ at three years. Conclusion A single programme for people with newly diagnosed type 2 diabetes mellitus showed no difference in biomedical or lifestyle outcomes at three years although there were sustained improvements in some illness beliefs. Trial registration Current Controlled Trials ISRCTN17844016.
登录
查看更多内容
影响因子：
168.9
作者：
Griffin, Simon J.;Borch-Johnsen, Knut;Davies, Melanie J.;Khunti, Kamlesh;Rutten, Guy E. H. M.;Sandbaek, Annelli;Sharp, Stephen J.;Simmons, Rebecca K.;van den Donk, Maureen;Wareham, Nicholas J.;Lauritzen, Torsten
通讯作者：
Lauritzen, Torsten
影响因子：
3.5
作者：
Deakin, T. A.;Cade, J. E.;Greenwood, D. C.
通讯作者：
Greenwood, D. C.
影响因子：
3.5
作者：
Khunti, K.;Skinner, T. C.;Davies, M. J.
通讯作者：
Davies, M. J.
影响因子：
158.5
作者：
Gaede, Peter;Lund-Andersen, Henrik;Pedersen, Oluf
通讯作者：
Pedersen, Oluf
影响因子：
158.5
作者：
Holman, Rury R.;Paul, Sanjoy K.;Neil, H. Andrew W.
通讯作者：
Neil, H. Andrew W.