Screening for Hepatocellular Carcinoma in Patients with Hepatitis B.

Screening for Hepatocellular Carcinoma in Patients with Hepatitis B.
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DOI:
10.3390/v13071318
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发表时间:
2021-07-08
期刊:
Viruses
影响因子:
--
通讯作者:
Congly SE
Congly SE
中科院分区:
其他
文献类型:
--
作者:
Sachar Y;Brahmania M;Dhanasekaran R;Congly SE

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慢性B型肝炎(CH B)感染是发生肝细胞癌(HCC)的重要危险因素。由于HCC与显著的发病率和死亡率相关,因此建议筛查HCC高风险的CHB患者,以改善这些结局。然而,关于谁来筛查以及多久筛查一次的筛查建议并不统一。确定HCC风险最高的患者将允许最佳利用卫生资源。在这篇综述中,我们评估了关于筛查CHB患者的HCC的文献,优化筛查依从性的策略,以及潜在的风险分层工具,以确定CHB患者发生HCC的高风险。
Chronic hepatitis B (CHB) infection is a significant risk factor for developing hepatocellular carcinoma (HCC). As HCC is associated with significant morbidity and mortality, screening patients with CHB at a high risk for HCC is recommended in an attempt to improve these outcomes. However, the screening recommendations on who to screen and how often are not uniform. Identifying patients at the highest risk of HCC would allow for the best use of health resources. In this review, we evaluate the literature on screening patients with CHB for HCC, strategies for optimizing adherence to screening, and potential risk stratification tools to identify patients with CHB at a high risk of developing HCC.
DOI: 10.1053/j.gastro.2011.12.061
发表时间: 2012-05
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