Interactions between serotonin transporter gene haplotypes and quality of mothers' parenting predict the development of children's noncompliance.
Interactions between serotonin transporter gene haplotypes and quality of mothers' parenting predict the development of children's noncompliance.
复制标题
血清素转运蛋白基因单倍型与母亲养育质量之间的相互作用可以预测儿童不顺从的发展。
DOI：
10.1037/a0025938
复制
发表时间：
2012
影响因子：
4
通讯作者：
Verrelli,BrianC
中科院分区：
文献类型：
--
作者：
Sulik,MichaelJ;Eisenberg,Nancy;Lemery-Chalfant,Kathryn;Spinrad,TracyL;Silva,KassondraM;Eggum,NatalieD;Betkowski,JenniferA;Kupfer,Anne;Smith,CynthiaL;Gaertner,Bridget;Stover,DarynA;Verrelli,BrianC
[更正通知：本文的错误见于《发展心理学》第49卷第(6)款(见《记录2013-18531-001》)。组1和组2的单倍型组合(在副标题SLC6A4单倍型组下)描述错误。第1组和第2组的真实单倍型组合在更正中给出。]将5-羟色胺转运体基因(SLC6A4)的LPR和STin2多态结合成单倍型，结合母亲的养育质量，预测18-54月龄儿童(N=138)不顺从和攻击性的初始水平和线性变化。在孩子18个月大时观察母亲的育儿行为质量，并在18-54个月大的时候每年收集非父母照顾者关于不遵守和攻击的报告。早期育儿质量只与LPR-S/STin2-10单倍型儿童的不依从斜率负相关，与18个月的不依从斜率只与单倍型不包括LPR-S的儿童负相关。这些发现支持这样的观点，即SLC6A4单倍型指示对父母养育质量变化的不同易感性，某些单倍型对支持性和非支持性环境都表现出更大的反应能力。这些不同的遗传背景可能反映了对育儿环境变化的进化反应。(心理信息数据库记录(C)2016 APA，版权所有)
[Correction Notice: An Erratum for this article was reported in Vol 49 (6) of Developmental Psychology (see record 2013-18531-001). The haplotype combinations for Group 1 and 2 (under the subheading SLC6A4 haplotype groups) are incorrectly described. The true haplotype combinations for Group 1 and 2 are given in the correction.] The LPR and STin2 polymorphisms of the serotonin transporter gene (SLC6A4) were combined into haplotypes that, together with quality of maternal parenting, were used to predict initial levels and linear change in children's (N= 138) noncompliance and aggression from age 18–54 months. Quality of mothers' parenting behavior was observed when children were 18 months old, and nonparental caregivers' reports of noncompliance and aggression were collected annually from 18 to 54 months of age. Quality of early parenting was negatively related to the slope of noncompliance only for children with the LPR-S/STin2-10 haplotype and to 18-month noncompliance only for children with haplotypes that did not include LPR-S. The findings support the notion that SLC6A4 haplotypes index differential susceptibility to variability in parenting quality, with certain haplotypes showing greater reactivity to both supportive and unsupportive environments. These different genetic backgrounds likely reflect an evolutionary response to variation in the parenting environment.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
登录
查看更多内容
影响因子：
3.3
作者：
J. K. Pritchard;Matthew Stephens;Peter Donnelly
通讯作者：
J. K. Pritchard;Matthew Stephens;Peter Donnelly
影响因子：
2.2
作者：
Gaertner, Bridget M.;Spinrad, Tracy L.;Eisenberg, Nancy
通讯作者：
Eisenberg, Nancy
影响因子：
3.5
作者：
H. Bleibtreu
通讯作者：
H. Bleibtreu
血清素转运基因
DOI：
--
发表时间：
2010
期刊：
影响因子：
--
作者：
D. Mrazek
通讯作者：
D. Mrazek
功能性血清素转运蛋白启动子基因多态性会增加不良儿童的多动症症状：与不良童年环境的相互作用
影响因子：
11.3
作者：
W. Retz;C. Freitag;P. Retz;D. Wenzler;M. Schneider;C. Kissling;J. Thome;M. Rösler
通讯作者：
M. Rösler