Impact of the first Covid-19 pandemic wave on first episode psychosis in Milan, italy.
Impact of the first Covid-19 pandemic wave on first episode psychosis in Milan, italy.
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DOI：
10.1016/j.psychres.2021.113802
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发表时间：
2021-04
影响因子：
11.3
通讯作者：
Brambilla P
中科院分区：
文献类型：
--
作者：
Esposito CM;D'Agostino A;Dell Osso B;Fiorentini A;Prunas C;Callari A;Oldani L;Fontana E;Gargano G;Viscardi B;Giordano B;D'Angelo S;Wiedenmann F;Macellaro M;Giorgetti F;Turtulici N;Gambini O;Brambilla P
正在进行的2019年冠状病毒病(新冠肺炎)大流行似乎增加了精神疾病的风险，直接由于病毒引起的炎症，或间接由于相关的心理社会压力，导致焦虑-抑郁和精神病症状的发展。本研究的目的是评估所有没有新冠肺炎感染的首发精神病(FEP)患者在米兰封锁后的前四个月住院的频率和特征。我们招募了62名在2020年3月8日至7月8日期间住院的患者，而不是2019年同期首次住院的患者。对两个亚组的社会人口学变量和发作的临床特征进行比较。2020年的FEP患者比2021年的FEP患者年龄大得多，并且药物滥用明显减少。有趣的是，2020年出现FEP的患者明显比2019年出现FEP的患者年龄大。这些数据与大流行期间对应激因素的更大脆弱性以及对可能导致脑损伤的新冠肺炎感染导致FEP的更大担忧是一致的。
The ongoing Corona Virus Disease 2019 (COVID–19) pandemic appears to increase risk for mental illness, either directly due to inflammation caused by the virus or indirectly due to related psychosocial stress, resulting in the development of both anxious-depressive and psychotic symptoms. The purpose of the present study was to assess the frequency and characteristics of all patients with First Episodes Psychosis (FEP) without COVID-19 infection hospitalized in the first four months since lockdown in Milan. We recruited sixty-two patients hospitalized between March 8 to July 8, 2020 versus those first hospitalized in the same period in 2019. The two subgroups were compared for sociodemographic variables and clinical characteristics of the episodes. Patients with FEP in 2020 were significantly older than patients with FEP in 2021, and presented with significantly less substances abuse. Interestingly, patients presenting with FEP in 2020 were significantly older than patients with FEP in 2019. These data are compatible with the greater vulnerability to stressful factors during the pandemic, as well as with the greater concern regarding a possible COVID-19 infection producing brain damage causing the FEP.
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影响因子：
4
作者：
Janssen, J;Beekman, ATF;Heeren, TJ
通讯作者：
Heeren, TJ
影响因子：
--
作者：
Hashem, Abdelhamid H;M, Nasreldin;Khalaf, Ola O
通讯作者：
Khalaf, Ola O
影响因子：
4.5
作者：
O'Donoghue, Brian;Lyne, John;Clarke, Mary
通讯作者：
Clarke, Mary
影响因子：
3.4
作者：
Ferrando, Stephen J.;Klepacz, Lidia;Bartell, Abraham
通讯作者：
Bartell, Abraham
DOI：
10.1111/j.2044-8341.1959.tb00467.x
发表时间：
1959-01-01
期刊：
BRITISH JOURNAL OF MEDICAL PSYCHOLOGY
影响因子：
--
作者：
HAMILTON, M
通讯作者：
HAMILTON, M