Sexual dysfunction in male Iraq and Afghanistan war veterans: association with posttraumatic stress disorder and other combat-related mental health disorders: a population-based cohort study.
Sexual dysfunction in male Iraq and Afghanistan war veterans: association with posttraumatic stress disorder and other combat-related mental health disorders: a population-based cohort study.
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DOI：
10.1111/jsm.12201
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发表时间：
2014-01
期刊：
影响因子：
--
通讯作者：
Seal KH
中科院分区：
文献类型：
--
作者：
Breyer BN;Cohen BE;Bertenthal D;Rosen RC;Neylan TC;Seal KH
心理健康障碍在美国、伊拉克和阿富汗战争退伍军人中很普遍。精神疾病，包括创伤后应激障碍（PTSD），无论是否使用精神药物，都可能增加男性性功能障碍的风险，威胁生活质量。我们试图确定男性伊拉克和阿富汗退伍军人性功能障碍的患病率和相关性。我们对405，275名男性伊拉克和阿富汗退伍军人进行了回顾性队列研究，他们是2001年10月7日至2009年9月30日美国退伍军人事务部医疗保健的新用户，并进行了2年随访。在调整了社会人口学和兵役特征、合并症和药物治疗后，我们确定了精神健康诊断和性功能障碍的独立关联。患有创伤后应激障碍的退伍军人更有可能有性功能障碍诊断，被开药治疗性功能障碍，或两者兼而有之（10.6%），相比之下，退伍军人有创伤后应激障碍以外的精神诊断（7.2%），或没有精神健康诊断（2.3%）。在一个完全校正的模型中，PTSD使性功能障碍的风险增加了三倍以上（校正的风险比= 3.61，95%CI = 3.48-3.75）。患有精神疾病的退伍军人，特别是PTSD，在处方精神病药物时性功能障碍的风险最高（校正风险比= 4.59，95%CI = 4.41-4.77）。在美国退伍军人中，精神健康障碍，特别是创伤后应激障碍，增加了性功能障碍的风险，而与精神药物的使用无关。
Mental health disorders are prevalent in the United States, Iraq, and Afghanistan war veterans. Mental illness, including posttraumatic stress disorder (PTSD) with or without psychiatric medications, can increase the risk for male sexual dysfunction, threatening quality of life. We sought to determine the prevalence and correlates of sexual dysfunction among male Iraq and Afghanistan veterans. We performed a retrospective cohort study of 405,275 male Iraq and Afghanistan veterans who were new users of U.S. Department of Veterans Affairs healthcare from October 7, 2001 to September 30, 2009 and had 2-year follow-up. We determined the independent association of mental health diagnoses and sexual dysfunction after adjusting for sociodemographic and military service characteristics, comorbidities, and medications. Veterans with PTSD were more likely to have a sexual dysfunction diagnosis, be prescribed medications for sexual dysfunction, or both (10.6%), compared with veterans having a mental diagnosis other than PTSD (7.2%), or no mental health diagnosis (2.3%). In a fully adjusted model, PTSD increased the risk of sexual dysfunction by more than threefold (adjusted risk ratio = 3.61, 95% CI = 3.48–3.75). Veterans with mental health disorders, particularly PTSD, were at the highest risk of sexual dysfunction when prescribed psychiatric medications (adjusted risk ratio = 4.59, 95% CI = 4.41–4.77). Among U.S. combat veterans, mental health disorders, particularly PTSD, increased the risk of sexual dysfunction independent of the use of psychiatric medications.
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影响因子：
1.2
作者：
Hutchinson, Jeffrey W.;Greene, Jeffery P.;Hansen, Shana L.
通讯作者：
Hansen, Shana L.
影响因子：
3.3
作者：
Letourneau, EJ;Schewe, PA;Frueh, BC
通讯作者：
Frueh, BC
影响因子：
2.1
作者：
Cosgrove, DJ;Gordon, Z;Monga, M
通讯作者：
Monga, M
影响因子：
3.3
作者：
Drescher, KD;Rosen, CS;Foy, DW
通讯作者：
Foy, DW
影响因子：
5.7
作者：
Litwin, MS;Nied, RJ;Dhanani, N
通讯作者：
Dhanani, N