An upper-level ontology for the biomedical domain.
An upper-level ontology for the biomedical domain.
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生物医学领域的高级本体论。
DOI：
10.1002/cfg.255
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发表时间：
2003
影响因子：
--
通讯作者：
McCray, AT
中科院分区：
文献类型：
--
作者：
McCray, AT
在美国国家医学图书馆，我们开发了统一医学语言系统(UMLS)，其目标是通过统一用于访问这些资源的词汇表，提供对大量生物医学资源的综合访问。UMLS目前将生物医学领域的约60个受控词汇表相互关联。UMLS的覆盖范围相当广泛，不仅包括临床医学中的许多概念，而且还包括大量适用于广泛生命科学领域的概念。为了为所有的UMLS概念提供一个总体的概念框架，我们开发了一个上层本体，称为UMLS语义网络。该语义网络通过其134种语义类型，为UMLS中表示的所有概念提供了一致的分类。语义类型之间的54个链接为网络提供结构，并代表生物医学领域中的重要关系。由于包含遗传信息的信息资源越来越多，UMLS在这一领域的覆盖范围正在扩大。我们最近整合了由NLM的国家生物技术信息中心开发的生物分类，目前我们正在与基因本体的开发者合作，以整合这一资源。随着额外的、标准的本体公开可用，我们希望将这些集成到UMLS构造中。
At the US National Library of Medicine we have developed the Unified Medical Language System (UMLS), whose goal it is to provide integrated access to a large number of biomedical resources by unifying the vocabularies that are used to access those resources. The UMLS currently interrelates some 60 controlled vocabularies in the biomedical domain. The UMLS coverage is quite extensive, including not only many concepts in clinical medicine, but also a large number of concepts applicable to the broad domain of the life sciences. In order to provide an overarching conceptual framework for all UMLS concepts, we developed an upper-level ontology, called the UMLS semantic network. The semantic network, through its 134 semantic types, provides a consistent categorization of all concepts represented in the UMLS. The 54 links between the semantic types provide the structure for the network and represent important relationships in the biomedical domain. Because of the growing number of information resources that contain genetic information, the UMLS coverage in this area is being expanded. We recently integrated the taxonomy of organisms developed by the NLM's National Center for Biotechnology Information, and we are currently working together with the developers of the Gene Ontology to integrate this resource, as well. As additional, standard, ontologies become publicly available, we expect to integrate these into the UMLS construct.
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影响因子：
7
作者：
Ashburner, M;Ball, CA;Yoon, J
通讯作者：
Yoon, J
影响因子：
5.4
作者：
Guarino, N
通讯作者：
Guarino, N
影响因子：
4.4
作者：
Wain, HM;Bruford, EA;Povey, S
通讯作者：
Povey, S
影响因子：
14.9
作者：
Wheeler, DL;Chappey, C;Rapp, BA
通讯作者：
Rapp, BA