Sialic acids in human health and disease.
Sialic acids in human health and disease.
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DOI:
10.1016/j.molmed.2008.06.002
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发表时间:
2008-08
影响因子:
13.6
通讯作者:
Varki A
中科院分区:
文献类型:
--
作者:
Varki A
The surfaces of all vertebrate cells are decorated with a dense and complex array of sugar chains, which are mostly attached to proteins and lipids. Most soluble secreted proteins are also similarly decorated with such glycans. Sialic acids are a diverse family of sugar units with a nine-carbon backbone that are typically found attached to the outermost ends of these chains. Given their location and ubiquitous distribution, sialic acids can mediate or modulate a wide variety of physiological and pathological processes. This review considers some examples of their established and newly emerging roles in aspects of human physiology and disease.
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影响因子:
6.7
作者:
Aspholm, Marina;Olfat, Farzad O.;Norden, Jenny;Sonden, Berit;Lundberg, Carina;Sjostrom, Rolf;Altraja, Siiri;Odenbreit, Stefan;Haas, Rainer;Wadstrom, Torkel;Engstrand, Lars;Semino-Mora, Cristina;Liu, Hui;Dubois, Andre;Teneberg, Susann;Arnqvist, Anna;Boren, Thomas
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Boren, Thomas
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4.3
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Chatterji, U;Sen, AK;Chowdhury, M
通讯作者:
Chowdhury, M
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Benatuil, L;Kaye, J;Iacomini, J
通讯作者:
Iacomini, J
影响因子:
64.8
作者:
CRICK, F
通讯作者:
CRICK, F
影响因子:
56.9
作者:
CHERESH, DA;REISFELD, RA;VARKI, AP
通讯作者:
VARKI, AP