Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis.
Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis.
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DOI：
10.4269/ajtmh.20-0869
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发表时间：
2020-11
期刊：
影响因子：
--
通讯作者：
Furment MM
中科院分区：
文献类型：
--
作者：
Mukherjee A;Ghosh R;Furment MM
COVID-19于二零一九年十二月在中国武汉被发现后，短短数月内已达到大流行状态。它是由SARS-CoV-2引起的，这是一种有包膜的β冠状病毒。这种感染通过炎症介质、内皮、微血管和可能的肝损伤以及病毒的组织嗜性的相互作用引起促血栓形成状态。这导致频繁的肺和脑血栓栓塞以及偶尔累及其他器官。我们介绍了一名71岁的男性，他最初出现2周的发热、咳嗽和呼吸急促，并被诊断为COVID-19肺炎。由于缺氧恶化，他需要再次住院，后来发现左肾动脉血栓形成伴左肾梗死，与升主动脉血栓相关。患者接受抗凝治疗，顺利恢复。我们认为，医生有高度的怀疑，以诊断和管理这种疾病的新表现。
Following its discovery in Wuhan, China, in December 2019, COVID-19 has attained pandemic status in mere months. It is caused by SARS-CoV-2, an enveloped beta coronavirus. This infection causes a prothrombogenic state by interplay of inflammatory mediators, and endothelial, microvascular, and possible hepatic damage and tissue tropism of the virus. This leads to frequent pulmonary and cerebral thromboembolism as well as occasional involvement of other organs. We present a 71-year-old man who initially presented with 2 weeks of fever, cough, and shortness of breath and was diagnosed with COVID-19 pneumonia. He required readmission due to worsened hypoxia and was later found to have left renal artery thrombosis with left kidney infarction, associated with an ascending aortic thrombus. He was anticoagulated and recovered uneventfully. We suggest that physicians have a high degree of suspicion to diagnose and manage the novel manifestations of this disease.
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DOI：
10.1056/nejmoa2022926
发表时间：
2020-11-19
期刊：
The New England journal of medicine
影响因子：
--
作者：
RECOVERY Collaborative Group;Horby P;Mafham M;Linsell L;Bell JL;Staplin N;Emberson JR;Wiselka M;Ustianowski A;Elmahi E;Prudon B;Whitehouse T;Felton T;Williams J;Faccenda J;Underwood J;Baillie JK;Chappell LC;Faust SN;Jaki T;Jeffery K;Lim WS;Montgomery A;Rowan K;Tarning J;Watson JA;White NJ;Juszczak E;Haynes R;Landray MJ
通讯作者：
Landray MJ
影响因子：
13.2
作者：
Post, Adrian;den Deurwaarder, Edwin S. G.;Berger, Stefan P.
通讯作者：
Berger, Stefan P.
影响因子：
4
作者：
Barnes, Geoffrey D.;Burnett, Allison;Minichiello, Tracy
通讯作者：
Minichiello, Tracy
影响因子：
3.5
作者：
Cavalcanti, D. D.;Raz, E.;Nelson, P. K.
通讯作者：
Nelson, P. K.
影响因子：
2.9
作者：
Ramacciotti, Eduardo;Agati, Leandro B.;Fareed, Jawed
通讯作者：
Fareed, Jawed