A Digital Gaming Intervention to Improve HIV Testing for Adolescents and Young Adults: Protocol for Development and a Pilot Randomized Controlled Trial.
A Digital Gaming Intervention to Improve HIV Testing for Adolescents and Young Adults: Protocol for Development and a Pilot Randomized Controlled Trial.
复制标题
DOI：
10.2196/29792
复制
发表时间：
2021-06-24
影响因子：
1.7
通讯作者：
Greenberg D
中科院分区：
文献类型：
--
作者：
Castel AD;Wilbourn B;Trexler C;D'Angelo LD;Greenberg D
美国结束艾滋病毒流行计划的两项策略是通过广泛检测来早期诊断感染，以及使用暴露前预防（PrEP）来预防新感染。这些策略对于受艾滋病毒影响尤为严重的青少年和年轻人 (AYA) 尤为重要，特别是如果他们被认为是黑人和/或女同性恋、男同性恋、双性恋、跨性别者、酷儿或质疑者以及其他人 (LGBTQ+)。这项研究将开发和测试一款交互式生活模拟游戏，玩家可以在其中扮演现实生活中的行为并获得他们的 HIV 风险概况，以改善华盛顿特区 13-24 岁 AYA 的 HIV 检测和 PrEP 获取。这项混合方法研究旨在确定 AYA 中交互式增强生活模拟游戏原型的可接受性，在一小群 AYA 中进行游戏干预试点测试，以确保游戏的可用性和可接受性，并在华盛顿特区针对有艾滋病毒风险的 AYA 进行的随机对照研究中评估游戏的功效。该研究方案将分三个阶段进行。形成阶段将涉及对居住在华盛顿地区的 AYA 进行调查和焦点小组 (n=64)。这些焦点小组将使研究人员能够了解年轻人对游戏增强的偏好。第二阶段将包括游戏干预的试点测试（n=10）。该试点测试将允许研究人员根据形成结果修改游戏，并与目标最终用户测试计划的招募和数据收集策略。第三阶段将包括在 300 个 AYA 中进行的随机对照研究，以检验生活模拟游戏与基于应用程序的 HIV 和 PrEP 教育材料相比，在改变 HIV 检测、知识、风险行为和 PrEP 获取方面的功效。自注册之日起 3 个月内，参与者可以无限制地使用生活模拟游戏或教育应用程序。研究评估将在入学时以及入学后 1、3 和 6 个月通过电子调查进行。 6 个月时，一部分干预参与者 (n=25) 将参与有关他们在研究中的经历的深入退出访谈。 2020 年 2 月 5 日收到机构审查委员会的批准。该项目目前正在招募形成阶段的参与者。这种互动生活模拟干预措施旨在增加华盛顿地区 AYA 的 HIV 检测和 PrEP 获取机会。在这种干预措施中，玩家可以扮演现实生活中的行为并获得他们的艾滋病毒风险概况，以促进艾滋病毒检测和 PrEP 寻求。这种干预措施具有巨大的潜力，可以提高 AYA 对 HIV 和 PrEP 的了解，提高与 HIV 检测和 PrEP 使用相关的积极性和自我效能，并减少通常妨碍参与 HIV 预防服务的个人和结构性障碍。 ClinicalTrials.gov NCT04917575； https://clinicaltrials.gov/ct2/show/NCT04917575 PRR1-10.2196/29792
Two strategies of the US Ending the HIV Epidemic initiative are early diagnosis of infections via widespread testing and prevention of new infections using pre-exposure prophylaxis (PrEP). These strategies are particularly important for adolescents and young adults (AYAs) who are disproportionately affected by HIV, particularly if they identify as Black and/or lesbian, gay, bisexual, transgender, queer or questioning, and others (LGBTQ+). This study will develop and test an interactive life-simulation game in which players can enact real-life behaviors and receive their HIV risk profile to improve HIV testing and PrEP access among AYAs aged 13-24 years in Washington, DC. This mixed methods study aims to determine the acceptability of an interactive, enhanced life-simulation game prototype among AYAs, conduct a pilot test of the gaming intervention among a small cohort of AYAs to ensure game usability and acceptability, and evaluate the efficacy of the game in a randomized controlled study with AYAs at risk for HIV in Washington, DC. This research protocol will be conducted in 3 phases. A formative phase will involve surveys and focus groups (n=64) with AYAs living in the DC area. These focus groups will allow researchers to understand youth preferences for game enhancement. The second phase will consist of a pilot test (n=10) of the gaming intervention. This pilot test will allow researchers to modify the game based on formative results and test the planned recruitment and data collection strategy with intended end users. The third phase will consist of a randomized controlled study among 300 AYAs to examine the efficacy of the life-simulation game compared with app-based HIV educational materials on HIV and PrEP in changing HIV testing, knowledge, risk behaviors, and PrEP access. Participants will have unlimited access to either the life-simulation game or the educational app for 3 months from the time of enrollment. Study assessments will occur at enrollment and at 1, 3, and 6 months post enrollment via e-surveys. At 6 months, a subset of intervention participants (n=25) will participate in in-depth exit interviews regarding their experience being in the study. Institutional review board approval was received on February 5, 2020. This project is currently recruiting participants for the formative phase. This interactive life-simulation intervention aims to increase HIV testing and PrEP access among AYAs in the DC area. In this intervention, players can enact real-life behaviors and receive their HIV risk profile to promote HIV testing and PrEP seeking. Such an intervention has great potential to improve knowledge of HIV and PrEP among AYAs, increase motivation and self-efficacy related to HIV testing and PrEP use, and decrease individual and structural barriers that often preclude engagement in HIV prevention services. ClinicalTrials.gov NCT04917575; https://clinicaltrials.gov/ct2/show/NCT04917575 PRR1-10.2196/29792
登录
查看更多内容
影响因子：
8
作者：
Flynn, Patricia M.;Aldrovandi, Grace M.;Schutze, Gordon E.
通讯作者：
Schutze, Gordon E.
影响因子：
8
作者：
Kato, Pamela M.;Cole, Steve W.;Pollock, Brad H.
通讯作者：
Pollock, Brad H.
少数民族青少年妇女的性风险行为和性传播感染健康素养。
影响因子：
2.2
作者：
Champion, Jane Dimmitt;Harlin, Badia;Collins, Jennifer L.
通讯作者：
Collins, Jennifer L.
DOI：
10.1177/109019818401100101
发表时间：
1984-01-01
期刊：
HEALTH EDUCATION QUARTERLY
影响因子：
--
作者：
JANZ, NK;BECKER, MH
通讯作者：
BECKER, MH
影响因子：
1.8
作者：
Carey, MP;Schroder, KEE
通讯作者：
Schroder, KEE