Biophysics of mitosis.

Biophysics of mitosis.
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DOI:
10.1017/s0033583512000017
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发表时间:
2012-05
影响因子:
6.1
通讯作者:
Ataullakhanov, Fazly I.
Ataullakhanov, Fazly I.
中科院分区:
生物学2区
文献类型:
--
作者:
McIntosh, J. Richard;Molodtsov, Maxim I.;Ataullakhanov, Fazly I.

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有丝分裂是真核细胞组织和分离染色体为细胞分裂做准备的过程。它是由主要由微管及其相关蛋白质组成的细胞机器完成的。本文从生物物理学的角度回顾了有丝分裂的文献,提请注意的组装和运动过程中需要做这个复杂的工作与精度。从最近的和旧的文献的工作被整合到相关的生物事件和实验,探索其机制的描述。具体的子过程的理论工作也进行了审查。我们的目标是提供一份文件,将暴露生物药理学家的魅力,这一相当惊人的过程,并为他们提供一个良好的背景,从他们可以追求自己的研究兴趣的主题。
Mitosis is the process by which eukaryotic cells organize and segregate their chromosomes in preparation for cell division. It is accomplished by a cellular machine composed largely of microtubules and their associated proteins. This article reviews literature on mitosis from a biophysical point of view, drawing attention to the assembly and motility processes required to do this complex job with precision. Work from both the recent and the older literature is integrated into a description of relevant biological events and the experiments that probe their mechanisms. Theoretical work on specific subprocesses is also reviewed. Our goal is to provide a document that will expose biophysicists to the fascination of this quite amazing process and provide them with a good background from which they can pursue their own research interests in the subject.
DOI: 10.1083/jcb.108.3.939
发表时间: 1989-03
期刊: The Journal of cell biology
影响因子: --
作者:
Geuens G;Hill AM;Levilliers N;Adoutte A;DeBrabander M
通讯作者: DeBrabander M
在冲浪蛤卵母细胞的减数分裂纺锤体中鉴定微管相关蛋白。
DOI: 10.1083/jcb.84.2.235
发表时间: 1980-02
影响因子: 7.8
作者:
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通讯作者: Murphy, D B