Pathophysiology and pharmacological management of pulmonary and cardiovascular features of COVID-19.
Pathophysiology and pharmacological management of pulmonary and cardiovascular features of COVID-19.
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DOI:
10.1016/j.yjmcc.2020.12.009
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发表时间:
2021-04
影响因子:
5
通讯作者:
Hadri L
中科院分区:
文献类型:
--
作者:
Hamouche W;Bisserier M;Brojakowska A;Eskandari A;Fish K;Goukassian DA;Hadri L
The first confirmed case of novel Coronavirus Disease 2019 (COVID-19) in the United States was reported on January 20, 2020. As of November 24, 2020, close to 12.2 million cases of COVID-19 was confirmed in the US, with over 255,958 deaths. The rapid transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), its unusual and divergent presentation has strengthened the status of COVID-19 as a major public health threat. In this review, we aim to 1- discuss the epidemiological data from various COVID-19 patient cohorts around the world and the USA as well the associated risk factors; 2- summarize the pathophysiology of SARS-CoV-2 infection and the underlying molecular mechanisms for the respiratory and cardiovascular manifestations; 3- highlight the potential treatments and vaccines as well as current clinical trials for COVID-19.
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DOI:
10.15557/pimr.2020.0003
发表时间:
2020-01-01
影响因子:
3.6
作者:
通讯作者:
--
影响因子:
6.4
作者:
Agostini ML;Andres EL;Sims AC;Graham RL;Sheahan TP;Lu X;Smith EC;Case JB;Feng JY;Jordan R;Ray AS;Cihlar T;Siegel D;Mackman RL;Clarke MO;Baric RS;Denison MR
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Denison MR
影响因子:
5.5
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通讯作者:
Deo, Rajat
影响因子:
39.3
作者:
Biere-Rafi, Sara;Hutten, Barbara A.;Kamphuisen, Pieter W.
通讯作者:
Kamphuisen, Pieter W.
影响因子:
158.5
作者:
Azhar, Esam I.;El-Kafrawy, Sherif A.;Madani, Tariq A.
通讯作者:
Madani, Tariq A.