Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study.
Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study.
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DOI：
10.3748/wjg.v23.i39.7160
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发表时间：
2017-10-21
影响因子：
4.3
通讯作者：
Phaosawasdi K
中科院分区：
文献类型：
--
作者：
Chaiteerakij R;Pan-Ngum W;Poovorawan K;Soonthornworasiri N;Treeprasertsuk S;Phaosawasdi K
为了确定胆管癌的潜在危险因素，我们确定了泰国5个不同地区胆管癌患者的特征。2008年至2013年期间诊断为胆管癌的所有患者均使用全国医院入院数据登记处（n = 39421）进行识别。提取基线特征、合并症和生存率。在研究期间，所有区域的年发病率保持稳定。大多数患者居住在东北部（62.8%），其次是北部（16.9%）、中部（12.3%）、曼谷（5.4%）和南部（n = 2.6%）地区（P < 0.0001）。胆管癌患者中糖尿病、肝硬化和慢性病毒性B/C型肝炎感染者明显多于非胆管癌患者（糖尿病：11.42% vs 5.28%;肝硬化：4.81% vs 0.92%; B型肝炎：0.74% vs 0.12%;丙型肝炎：0.50% vs 0.10%，P均< 0.0001）。总体1年死亡率为81.7%，随时间推移呈稳定趋势。在泰国人群中，糖尿病和慢性肝病可能与胆管癌有关。
To identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand. All patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admission Data registry (n = 39421). Baseline characteristics, comorbidities and survival were abstracted. The annual incidence during the study period was stable in all regions. Most patients lived in the Northeast (62.8%), followed by the North (16.9%), Central (12.3%), Bangkok (5.4%), and South (n = 2.6%) regions (P < 0.0001). Significantly more cholangiocarcinoma patients had diabetes, cirrhosis, and chronic viral hepatitis B/C infection than non-cholangiocarcinoma participants (diabetes: 11.42% vs 5.28%; cirrhosis: 4.81% vs 0.92%; hepatitis B: 0.74% vs 0.12%; and hepatitis C: 0.50% vs 0.10%, P < 0.0001 for all, respectively). The overall 1-year mortality rate was 81.7%, with a stable trend over time. Diabetes and chronic liver diseases may be associated with cholangiocarcinoma in the Thai population.
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影响因子：
15.8
作者：
Sripa, Banchob;Kaewkes, Sasithorn;Sithithaworn, Paiboon;Mairiang, Eimorn;Laha, Thewarach;Smout, Michael;Pairojkul, Chawalit;Bhudhisawasdi, Vajaraphongsa;Tesana, Smarn;Thinkamrop, Bandit;Bethony, Jeffrey M.;Loukas, Alex;Brindley, Paul J.
通讯作者：
Brindley, Paul J.
影响因子：
2.7
作者：
Sripa, Banchob;Tangkawattana, Sirikachorn;Laha, Thewarach;Kaewkes, Sasithorn;Mallory, Frank F.;Smith, John F.;Wilcox, Bruce A.
通讯作者：
Wilcox, Bruce A.
影响因子：
29.4
作者：
Ilyas SI;Gores GJ
通讯作者：
Gores GJ
影响因子：
4.3
作者：
Lee, Ban Seok;Park, Eun-Cheol;Roh, Jaehoon
通讯作者：
Roh, Jaehoon
DOI：
10.1111/j.1440-1746.2012.07207.x
发表时间：
2012-10-01
影响因子：
4.1
作者：
Li, Min;Li, Jinzheng;Gong, Jianping
通讯作者：
Gong, Jianping