Sympathetic Nervous System Contributions to Hypertension: Updates and Therapeutic Relevance.
Sympathetic Nervous System Contributions to Hypertension: Updates and Therapeutic Relevance.
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DOI:
10.1016/j.cjca.2020.03.003
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发表时间:
2020-05
期刊:
影响因子:
--
通讯作者:
Stocker SD
中科院分区:
文献类型:
--
作者:
DeLalio LJ;Sved AF;Stocker SD
The sympathetic nervous system plays a pivotal role in the long-term regulation of arterial blood pressure through the ability of the central nervous system to integrate neurohumoral signals and differentially regulate sympathetic neural input to specific end organs. Part 1 of this review will discuss neural mechanisms of salt-sensitive hypertension, obesity-induced hypertension, and the ability of prior experiences to sensitize autonomic networks. Part 2 of this review focuses on new therapeutic advances to treat resistant hypertension including renal denervation and carotid baroactivation. Both advances lower arterial blood pressure by reducing sympathetic outflow. We discuss potential mechanisms and areas of future investigation to target the sympathetic nervous system.
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影响因子:
2.5
作者:
Foss JD;Fiege J;Shimizu Y;Collister JP;Mayerhofer T;Wood L;Osborn JW
通讯作者:
Osborn JW
DOI:
10.1152/ajpregu.00408.2015
发表时间:
2016-02-01
影响因子:
2.8
作者:
Foss, Jason D.;Fink, Gregory D.;Osborn, John W.
通讯作者:
Osborn, John W.
影响因子:
8.3
作者:
BERECEK, KH;BARRON, KW;BRODY, MJ
通讯作者:
BRODY, MJ
影响因子:
8.3
作者:
Carey, Robert M.;Sakhuja, Swati;Muntner, Paul
通讯作者:
Muntner, Paul
DOI:
10.1161/hypertensionaha.111.00474
发表时间:
2013-04
期刊:
Hypertension (Dallas, Tex. : 1979)
影响因子:
--
作者:
Foss JD;Fink GD;Osborn JW
通讯作者:
Osborn JW