Antibacterial activity composition of the fermentation broth of Streptomyces djakartensis NW35.
Antibacterial activity composition of the fermentation broth of Streptomyces djakartensis NW35.
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DOI：
10.3390/molecules18032763
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发表时间：
2013-03-01
期刊：
影响因子：
--
通讯作者：
Wu W
中科院分区：
文献类型：
--
作者：
Zhang W;Wei S;Zhang J;Wu W
新化合物Z-4-2是从Streptomyces djakartensis NW 35的发酵液中分离得到的，它与已知化合物N-乙酰色胺（Z-9-2）一起通过生物活性导向分离得到。其化学结构经NMR和MS分析确定为（E）-2-甲氧基-1，4-萘醌-1-肟（Z-4-2）。用滤纸法测定了它们的抗菌活性。结果表明，这些化合物具有明显的抗菌活性。
The new compound Z-4-2 was isolated from the fermentation broth of Streptomyces djakartensis NW35, together with the known compound N-acetyltryptamine (Z-9-2) by bioassay-guided fractionation. Its chemical structure was elucidated as (E)-2-methoxy-1,4 naphthoquinone-1-oxime (Z-4-2) mainly by NMR analyses and MS spectral data. Their antibacterial activities against bacteria were evaluated by the filter paper method. The results of indicated that these compounds possess significant antibacterial activities.
影响因子：
4.4
作者：
JUHNKE, ME;MATHRE, DE;SANDS, DC
通讯作者：
SANDS, DC
影响因子：
11.8
作者：
Spellberg, Brad;Guidos, Robert;Edwards, John, Jr.
通讯作者：
Edwards, John, Jr.