Computer-based inhibitory control training in children with Attention-Deficit/Hyperactivity Disorder (ADHD): Evidence for behavioral and neural impact.
Computer-based inhibitory control training in children with Attention-Deficit/Hyperactivity Disorder (ADHD): Evidence for behavioral and neural impact.
复制标题
DOI：
10.1371/journal.pone.0241352
复制
发表时间：
2020
期刊：
影响因子：
3.7
通讯作者：
Sheridan MA
中科院分区：
文献类型：
--
作者：
Meyer KN;Santillana R;Miller B;Clapp W;Way M;Bridgman-Goines K;Sheridan MA
Attention-deficit hyperactivity disorder (ADHD) is the most commonly diagnosed psychological disorder of childhood. Medication and cognitive behavioral therapy are effective treatments for many children; however, adherence to medication and therapy regimens is low. Thus, identifying effective adjunct treatments is imperative. Previous studies exploring computerized training programs as supplementary treatments have targeted working memory or attention. However, many lines of research suggest inhibitory control (IC) plays a central role in ADHD pathophysiology, which makes IC a potential intervention target. In this randomized control trial (NCT03363568), we target IC using a modified stop-signal task (SST) training designed by NeuroScouting, LLC in 40 children with ADHD, aged 8 to 11 years. Children were randomly assigned to adaptive treatment (n = 20) or non-adaptive control (n = 20) with identical stimuli and task goals. Children trained at home for at least 5 days a week (about 15m/day) for 4-weeks. Relative to the control group, the treatment group showed decreased relative theta power in resting EEG and trending improvements in parent ratings of attention (i.e. decreases in inattentive behaviors). Both groups showed improved SST performance. There was not evidence for treatment effects on hyperactivity or teacher ratings of symptoms. Results suggest training IC alone has potential to positively impact symptoms of ADHD and provide evidence for neural underpinnings of this impact (change in theta power; change in N200 latency). This shows promising initial results for the use of computerized training of IC in children with ADHD as a potential adjunct treatment option for children with ADHD.
登录
查看更多内容
影响因子：
6.7
作者：
Charach, Alice;Fernandez, Rebeca
通讯作者：
Fernandez, Rebeca
DOI：
10.1111/j.1469-7610.2006.01671.x
发表时间：
2006-10-01
影响因子：
7.6
作者：
Dickstein, Steven G.;Bannon, Katie;Milham, Michael P.
通讯作者：
Milham, Michael P.
影响因子：
3
作者：
Arns, Martijn;Conners, C. Keith;Kraemer, Helena C.
通讯作者：
Kraemer, Helena C.
影响因子：
2.6
作者：
EIMER, M
通讯作者：
EIMER, M
影响因子：
3.2
作者：
de Oliveira Rosa, Virginia;Rosa Franco, Alexandre;Paim Rohde, Luis Augusto
通讯作者：
Paim Rohde, Luis Augusto