SURFACE ULTRASTRUCTURE OF HUMAN ARTERIES WITH SPECIAL REFERENCE TO THE EFFECTS OF SMOKING
SURFACE ULTRASTRUCTURE OF HUMAN ARTERIES WITH SPECIAL REFERENCE TO THE EFFECTS OF SMOKING
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人体动脉表面超微结构，特别参考吸烟的影响
DOI：
10.1111/j.1699-0463.1979.tb00043.x
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
H. Hansson
中科院分区：
文献类型：
--
作者：
A. Bylock;G. Bondjers;I. Jansson;H. Hansson
应用扫描电镜观察了20例妇女子宫动脉表面的超微结构。在子宫切除术中切除子宫后不久，切除标本并在压力下固定。选择了两组患者：非吸烟者和每天吸烟超过15支的女性。在不了解患者吸烟习惯的情况下，评估了7种不同形态学标准的患病率。内皮细胞边界清楚，其长轴与动脉长轴平行。细胞核轻微隆起至管腔内，细胞边缘可见一排排微绒毛。吸烟者动脉中沿细胞边界的细胞间和细胞内孔沿着更常见，而非吸烟者动脉细胞表面的微绒毛更常见。这些差异可能与细胞损伤有关。先前的研究表明，损伤细胞中的孔比未损伤细胞中的孔更频繁，而损伤细胞的表面通常比未损伤细胞的表面更光滑。因此，这些数据可能表明吸烟可导致人类内皮损伤。
The surface ultrastructure of uterine arteries from 20 women was studied with scanning electron microscopy. Specimens were excised and fixed under pressure shortly after removal of the uterus during hysterectomy. Two groups of patients were selected: non‐smokers and women who smoked more than 15 cigarettes a day. The prevalence of seven different morphological criteria was evaluated without knowledge of the smoking habits of the patients. Endothelial cells were usually well demarcated and distributed with their length axis parallel to that of the artery. The cell nucleus was revealed by a gentle bulging into the lumen, and cell borders by the presence of rows of microvilli. Inter‐ and intracellular holes along the cell borders were more common in arteries from smokers, whereas microvilli were more common on the cell surfaces of arteries from non‐smokers. These differences might be related to cell injury. Previous studies indicate that holes are more frequent in injured than in non‐injured cells, whereas the surface of injured cells is often smoother than that of non‐injured cells. Therefore, these data may by taken to suggest that smoking can lead to endothelial injury in man.
DOI：
10.1007/bf00429607
发表时间：
1982
期刊：
Virchows Archiv. A, Pathological anatomy and histology
影响因子：
--
作者：
Zand,T;Underwood,JM;Nunnari,JJ;Majno,G;Joris,I
通讯作者：
Joris,I