Timeliness and completeness of measles vaccination among children in rural areas of Guangxi, China: A stratified three-stage cluster survey.
Timeliness and completeness of measles vaccination among children in rural areas of Guangxi, China: A stratified three-stage cluster survey.
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广西农村儿童麻疹疫苗接种及时性和完整性：分层三阶段整群调查
DOI：
10.1016/j.je.2016.08.006
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发表时间：
2017-07
影响因子：
4.7
通讯作者：
Dong A
中科院分区：
文献类型：
--
作者：
Tang X;Geater A;McNeil E;Zhou H;Deng Q;Dong A
2013年和2014年，中国西南地区含麻疹疫苗（MCV）覆盖率高的地区广西农村发生了大规模麻疹疫情。本研究旨在估计广西农村18-54月龄儿童MCV的及时接种覆盖率、及时完全接种覆盖率和中位延迟期。根据2011-2013年麻疹发病率的四分位数，于2015年6月至8月进行了分层三阶段聚类调查。采用加权估计和有限群体校正，计算疫苗接种覆盖率和95%置信区间（ci）。加权Kaplan-Meier分析用于估计第一剂（MCV1）和第二剂（MCV2）疫苗的中位延迟期。共有1216名儿童接受了调查。MCV1的及时疫苗接种率为58.4% (95% CI, 54.9% ~ 62.0%)， MCV2的及时疫苗接种率为76.9% （95% CI, 73.6% ~ 80.0%）。及时和完全疫苗接种覆盖率为47.4% （95% CI, 44.0%-51.0%）。MCV1的中位延迟期为32 （95% CI, 27-38）天，MCV2的中位延迟期为159 （95% CI, 118-195）天。广西农村儿童麻疹疫苗接种及时性和完全性较低，中位延迟期较长。将及时性和完整性纳入官方常规疫苗接种覆盖率统计有助于评估中国的疫苗接种覆盖率。麻疹疫苗接种的及时性和完整性较低。广西儿童麻疹疫苗接种的中位延迟期较长。麻疹发病率较高的地区未及时覆盖率较高。
Large-scale outbreaks of measles occurred in 2013 and 2014 in rural Guangxi, a region in Southwest China with high coverage for measles-containing vaccine (MCV). This study aimed to estimate the timely vaccination coverage, the timely-and-complete vaccination coverage, and the median delay period for MCV among children aged 18–54 months in rural Guangxi. Based on quartiles of measles incidence during 2011–2013, a stratified three-stage cluster survey was conducted from June through August 2015. Using weighted estimation and finite population correction, vaccination coverage and 95% confidence intervals (CIs) were calculated. Weighted Kaplan–Meier analyses were used to estimate the median delay periods for the first (MCV1) and second (MCV2) doses of the vaccine. A total of 1216 children were surveyed. The timely vaccination coverage rate was 58.4% (95% CI, 54.9%–62.0%) for MCV1, and 76.9% (95% CI, 73.6%–80.0%) for MCV2. The timely-and-complete vaccination coverage rate was 47.4% (95% CI, 44.0%–51.0%). The median delay period was 32 (95% CI, 27–38) days for MCV1, and 159 (95% CI, 118–195) days for MCV2. The timeliness and completeness of measles vaccination was low, and the median delay period was long among children in rural Guangxi. Incorporating the timeliness and completeness into official routine vaccination coverage statistics may help appraise the coverage of vaccination in China. The timeliness and completeness of measles vaccination was low. The median delay period of measles vaccination was long among Guangxi children. Regions with higher measles incidence had higher rates of untimely coverage.
影响因子：
4.5
作者：
Mayxay M;Khomthilat T;Souvannasing P;Phounesavath K;Vorasane B;Keomany S;Douangdala P;Philavong K;Srour L;Newton PN
通讯作者：
Newton PN