Factors associated with a measles outbreak in children admitted at Mahosot Hospital, Vientiane, Laos.
Factors associated with a measles outbreak in children admitted at Mahosot Hospital, Vientiane, Laos.
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DOI：
10.1186/1471-2458-7-193
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发表时间：
2007-08-04
影响因子：
4.5
通讯作者：
Newton PN
中科院分区：
文献类型：
--
作者：
Mayxay M;Khomthilat T;Souvannasing P;Phounesavath K;Vorasane B;Keomany S;Douangdala P;Philavong K;Srour L;Newton PN
2002年和2003年，老挝许多省份（包括万象）爆发了大规模麻疹疫情。因此，我们进行了一项研究，以确定万象 Mahosot 医院收治的儿童中与麻疹相关的危险因素。对 50 名临床麻疹儿童进行了一项回顾性病例对照研究，这些儿童的年龄和性别与与病例同村的 50 名健康儿童（从未出现过热疹）相匹配。与对照组相比，临床麻疹组完全免疫的儿童比例显着较低[13/50 (26%) vs 34/50 (68%)，P < 0.001）。与健康对照组相比，临床麻疹组在 9-23 个月大时接受麻疹疫苗的儿童比例显着较低 [12/50 (24%) vs 24/50 (48%)，P = 0.01）。病例和对照之间的家庭教育和社会经济状况没有显着差异（P > 0.05）。这些结果强调了老挝加强麻疹免疫覆盖率的重要性。加强大规模、广泛的高第二剂量覆盖范围的运动可能是老挝预防麻疹进一步爆发的关键措施（192字）。
In 2002 and 2003 there were large outbreaks of measles in many provinces of Laos, including in Vientiane. We therefore conducted a study to determine risk factors associated with measles amongst children admitted at Mahosot Hospital, Vientiane. A retrospective case-control study was conducted in 50 children with clinical measles who were matched by age and sex with 50 healthy children (who had never had a febrile rash) living in the same villages as the cases. The proportion of children with complete immunizations was significantly lower in the group with clinical measles compared to the controls [13/50 (26%) vs 34/50 (68%), P < 0.001). The percentage of children who had received measles vaccine at 9–23 months of age was significantly lower in the group with clinical measles compared to the healthy controls [12/50 (24%) vs 24/50 (48%), P = 0.01). The family educational and socio-economic status did not differ significantly (P > 0.05) between cases and controls. These results emphasize the importance of intensification of measles immunization coverage in Laos. The strengthening of campaigns with large, widespread high second dose coverage is likely to be a key measure to prevent further measles outbreaks in Laos (192 words).
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影响因子：
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作者：
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通讯作者：
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作者：
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通讯作者：
TAYLOR, B