Psychosocial and biological risk factors of anxiety disorders in adolescents: a TRAILS report.
Psychosocial and biological risk factors of anxiety disorders in adolescents: a TRAILS report.
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DOI：
10.1007/s00787-020-01669-3
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发表时间：
2021-12
影响因子：
6.4
通讯作者：
Oldehinkel AJ
中科院分区：
文献类型：
--
作者：
Narmandakh A;Roest AM;de Jonge P;Oldehinkel AJ
焦虑症是青少年心理健康中常见的问题。以前的研究同时只调查了有限数量的焦虑症发展的危险因素。通过同时调查多种因素，可以对焦虑症的病因有更全面的了解。因此，我们评估了青春期前的社会人口、家庭、心理社会和生物因素及其与青春期焦虑症发病的关系。这项研究是在跟踪青少年个人生活调查(TRILS)的1584名荷兰参与者中进行的。在基线(10-12岁)时评估了潜在的危险因素，包括社会人口(性别、社会经济状况)、家庭(父母焦虑和抑郁)、心理社会(童年逆境、气质)和生物(体重指数、心率、血压、皮质醇)变量。焦虑症在大约19岁时通过综合国际诊断访谈(CIDI)进行评估。以焦虑症的发病为因变量，以上述可能的危险因素为预测因素，进行单因素和多因素Logistic回归分析。在总样本中，25.7%的人在19岁时被终生诊断为焦虑症。焦虑症在女孩中的流行程度是男孩的两倍。多因素Logistic回归分析显示，女性(OR = 2.38，p <； .01)、父母抑郁和焦虑(OR = 1.34，p = .04)、气质挫折(OR = 1.31，p = .02)和努力控制力差(OR = 0.76，p = .01)是预测焦虑症的独立危险因素。我们发现生物因素和焦虑症之间没有关联。在排除了12岁之前出现焦虑症的青少年后，女性是焦虑症的唯一重要预测因素。女性是焦虑症发病的最强预测者。心理和父母的心理病理因素增加了焦虑症的诊断风险，但程度较小。生物因素(心率、血压、皮质醇和体重指数)，至少在本研究中被测量，不太可能成为焦虑预防和干预策略的有用工具。本文的在线版本(10.1007/s00787-020-01669-3)包含向授权用户提供的补充材料。
Anxiety disorders are a common problem in adolescent mental health. Previous studies have investigated only a limited number of risk factors for the development of anxiety disorders concurrently. By investigating multiple factors simultaneously, a more complete understanding of the etiology of anxiety disorders can be reached. Therefore, we assessed preadolescent socio-demographic, familial, psychosocial, and biological factors and their association with the onset of anxiety disorders in adolescence. This study was conducted among 1584 Dutch participants of the TRacking Adolescents’ Individual Lives Survey (TRAILS). Potential risk factors were assessed at baseline (age 10–12), and included socio-demographic (sex, socioeconomic status), familial (parental anxiety and depression), psychosocial (childhood adversity, temperament), and biological (body mass index, heart rate, blood pressure, cortisol) variables. Anxiety disorders were assessed at about age 19 years through the Composite International Diagnostic Interview (CIDI). Univariate and multivariate logistic regression analyses were performed with onset of anxiety disorder as a dependent variable and the above-mentioned putative risk factors as predictors. Of the total sample, 25.7% had a lifetime diagnosis of anxiety disorder at age 19 years. Anxiety disorders were twice as prevalent in girls as in boys. Multivariate logistic regression analysis showed that being female (OR = 2.38, p < .01), parental depression and anxiety (OR = 1.34, p = .04), temperamental frustration (OR = 1.31, p = .02) and low effortful control (OR = 0.76, p = .01) independently predicted anxiety disorders. We found no associations between biological factors and anxiety disorder. After exclusion of adolescents with an onset of anxiety disorder before age 12 years, being female was the only significant predictor of anxiety disorder. Being female was the strongest predictor for the onset of anxiety disorder. Psychological and parental psychopathology factors increased the risk of diagnosis of anxiety, but to a lesser extent. Biological factors (heart rate, blood pressure, cortisol, and BMI), at least as measured in the present study, are unlikely to be useful tools for anxiety prevention and intervention strategies. The online version of this article (10.1007/s00787-020-01669-3) contains supplementary material, which is available to authorized users.
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DOI：
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发表时间：
2014-01
影响因子：
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