Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions.

Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions.
复制标题

DOI:
10.1136/jnnp-2013-307539
复制
发表时间:
2014-10
期刊:
Journal of neurology, neurosurgery, and psychiatry
影响因子:
--
通讯作者:
Zetterberg H
Zetterberg H
中科院分区:
其他
文献类型:
--
作者:
Magdalinou N;Lees AJ;Zetterberg H

文献摘要

参考文献

被引文献

相似文献

帕金森病包括一组异质性的神经退行性疾病,其显示出显著的临床和病理重叠。准确的诊断仍然主要依赖于临床敏锐性;病理诊断仍然是金标准。迫切需要生物标志物来诊断帕金森病,特别是在诊断最困难的早期阶段。在这篇综述中,将讨论几个最有前途的脑脊液候选标记物。它们的优点和局限性将与该领域的未来发展一起考虑。
Parkinsonian diseases comprise a heterogeneous group of neurodegenerative disorders, which show significant clinical and pathological overlap. Accurate diagnosis still largely relies on clinical acumen; pathological diagnosis remains the gold standard. There is an urgent need for biomarkers to diagnose parkinsonian disorders, particularly in the early stages when diagnosis is most difficult. In this review, several of the most promising cerebrospinal fluid candidate markers will be discussed. Their strengths and limitations will be considered together with future developments in the field.
DOI: 10.1212/01.wnl.0000335941.68602.39
发表时间: 2008-11-25
期刊: NEUROLOGY
影响因子: 9.9
作者:
Borroni, B.;Malinverno, M.;Padovani, A.
通讯作者: Padovani, A.
DOI: 10.1002/mds.22594
发表时间: 2009-11-15
期刊: MOVEMENT DISORDERS
影响因子: 8.6
作者:
Compta, Yaroslau;Marti, Maria J.;Tolosa, Eduardo
通讯作者: Tolosa, Eduardo
DOI: 10.3389/fneur.2012.00187
发表时间: 2012
影响因子: 3.4
作者:
Constantinescu R;Mondello S
通讯作者: Mondello S
DOI: 10.1136/jnnp.2009.199950
发表时间: 2010-10-01
影响因子: 11
作者:
Alves, Guido;Bronnick, Kolbjorn;Mulugeta, Ezra
通讯作者: Mulugeta, Ezra
DOI: 10.1212/01.wnl.0000249130.63615.cc
发表时间: 2006-12-12
期刊: NEUROLOGY
影响因子: 9.9
作者:
Ballard, C.;Ziabreva, I.;Aarsland, D.
通讯作者: Aarsland, D.