Adverse birth outcome case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review protocol.

Adverse birth outcome case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review protocol.
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DOI:
10.1136/bmjopen-2023-072417
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发表时间:
2023-06-26
期刊:
影响因子:
2.9
通讯作者:
Slogrove, Amy L.
Slogrove, Amy L.
中科院分区:
医学3区
文献类型:
--
作者:
Dube, Kopano Rebaona;Powis, Kathleen M.;McCaul, Michael;de Beer, Shani Tamlyn;Slogrove, Amy L.

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全球抗逆转录病毒治疗时代导致新感染艾滋病毒的儿童人数下降,而感染艾滋病毒但未感染的儿童人数增加。这一转变促使人们开展广泛的研究,重点关注高浓缩铀儿童的健康和生存结果。研究结果,特别是与不良出生结果有关的研究结果,是不同的,不确定的,并不总是可以推广的。因此,本范围审查的目的是(1)识别和提取不良出生结局术语“低出生体重”、“小于胎龄儿”、“死产”和“早产”的定义;(2)比较按(a)时间段和(B)研究国家背景提取出生结局定义的研究的特征(3)利用内容分析绘制和描述所用定义的时间和地理分布图,并构建其演变的逻辑模型。PubMed/MEDLINE、Scopus、Web of Science、科克伦图书馆和CINHAL/EBSCOhost的在线数据库将用于识别2011年至2022年的已发表文献和灰色文献,以确定不良出生结局术语“低出生体重”、“小于胎龄儿”、“死产”和“早产”的定义。将采用三步流程(1)重复删除,(2)标题和摘要筛选,以及(3)全文筛选来选择纳入的研究。抽取的数据将用于进行比较分析、内容分析并构建逻辑模型。该综述将用于围绕特定不良出生结局的统一定义的制定达成共识。我们的传播计划包括演讲、出版物以及发展信息图表和资源中心。该研究由斯泰伦博斯大学人类研究伦理委员会批准。
The global antiretroviral therapy era has led to a decline in the number of children newly acquiring HIV and an increase in the number of children who are HIV-exposed and uninfected (HEU). This shift has prompted extensive research focussing on health and survival outcomes of children who are HEU. Study findings, particularly in relation to adverse birth outcomes, have been disparate, inconclusive and have not always been generalisable. Thus, the objectives of this scoping review are (1) to identify and extract definitions used for the adverse birth outcome terms ‘low birth weight’, ‘small for gestational age’, ‘stillbirth’ and ‘preterm birth’; (2) to compare the characteristics of studies from which birth outcome definitions were extracted by (a) temporal periods and (b) study country setting (high-income vs low-income and middle-income countries); (3) to use content analysis to map and describe the temporal and geographic distribution of the definitions used and construct a logical model of their evolution. The online databases of PubMed/MEDLINE, Scopus, Web of Science, Cochrane Library and CINHAL/EBSCOhost will be used to identify published and grey literature from 2011 to 2022 to identify definitions for the adverse birth outcome terms ‘low birth weight’, ‘small for gestational age’, ‘stillbirth’ and ‘preterm birth’. A three-step process of (1) duplicate removal, (2) title and abstract screening and (3) full text screening will be used to select included studies. The extracted data will be used to conduct a comparative analysis, content analysis and construct a logic model. This review will be used to inform a consensus process around the development of harmonised definitions for the specified adverse birth outcomes. Our dissemination plan includes presentations, publications as well as the development infographics and a resource hub. The study is approved by the Human Research Ethics Committee of Stellenbosch University.
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发表时间: 2021-03-29
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发表时间: 2011-08-15
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