The Medial Temporal Lobe Is Critical for Spatial Relational Perception
The Medial Temporal Lobe Is Critical for Spatial Relational Perception
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内侧颞叶对于空间关系感知至关重要
DOI：
10.1162/jocn_a_01583
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发表时间：
2020
影响因子：
3.2
通讯作者：
Aly, Mariam
中科院分区：
文献类型：
--
作者：
Ruiz, Nicholas A.;Meager, Michael R.;Agarwal, Sachin;Aly, Mariam
内侧颞叶（MTL）传统上被认为是一个专门用于长期记忆的系统。最近的研究对这一观点提出了挑战，表明该区域可以参与长期记忆之外的许多认知领域，包括感知和注意力。颞叶颞叶（尤其是海马体）对认知有广泛贡献的一个潜在原因是，它包含关系表征——经验的多维特征表征及其彼此之间的独特关系——在许多不同的认知领域都很有用。在这里，我们探讨了海马体/MTL通过关系表征在注意和感知中起关键作用的假设。我们比较了MTL损伤的人类参与者与年龄和教育程度匹配的健康个体在关系处理需求不同的注意力任务上的差异。在每次试验中，参与者观看两幅图像（有绘画的房间）。在“相似房间”试验中，他们从不同的角度判断房间是否有相同的空间布局。在“相似艺术”试验中，他们判断这些画是否出自同一画家之手。在“相同”试验中，参与者只需要识别相同的画作或房间。MTL病变患者在类似的房间任务中表现出明显的选择性损伤。这项工作进一步证明了海马体/MTL通过其关系表征和空间表征在认知中发挥着无处不在的作用，并强调了其对受益于注意力的快速感知过程的重要贡献。
The medial temporal lobe (MTL) is traditionally considered to be a system that is specialized for long-term memory. Recent work has challenged this notion by demonstrating that this region can contribute to many domains of cognition beyond long-term memory, including perception and attention. One potential reason why the MTL (and hippocampus specifically) contributes broadly to cognition is that it contains relational representations—representations of multidimensional features of experience and their unique relationship to one another—that are useful in many different cognitive domains. Here, we explore the hypothesis that the hippocampus/MTL plays a critical role in attention and perception via relational representations. We compared human participants with MTL damage to healthy age- and education-matched individuals on attention tasks that varied in relational processing demands. On each trial, participants viewed two images (rooms with paintings). On “similar room” trials, they judged whether the rooms had the same spatial layout from a different perspective. On “similar art” trials, they judged whether the paintings could have been painted by the same artist. On “identical” trials, participants simply had to detect identical paintings or rooms. MTL lesion patients were significantly and selectively impaired on the similar room task. This work provides further evidence that the hippocampus/MTL plays a ubiquitous role in cognition by virtue of its relational and spatial representations and highlights its important contributions to rapid perceptual processes that benefit from attention.
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发表时间：
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期刊：
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